ArticlePediatrics2022
Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Contemporary Organ Dysfunction Criteria: Executive Summary.
Open access · greenAbstract readConsensus Statement
In one paragraph
Article in Pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 5 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 5 pooled it
9.3field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed, 5 syntheses or guidelines pooled it, 80 citations in OpenAlex.
- Immune System Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference.Pediatrics · 2022Pooled it
- Renal Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference.Pediatrics · 2022Pooled it
- Scoring Systems for Organ Dysfunction and Multiple Organ Dysfunction: The PODIUM Consensus Conference.Pediatrics · 2022Pooled it
- Cardiovascular Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference.Pediatrics · 2022Pooled it
- Endothelial Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference.Pediatrics · 2022Pooled it
- Time from acute kidney injury to continuous renal replacement therapy and outcomes in critically ill children.Clinical kidney journal · 2026Article
- Respiratory-Support Phenotypes and In-Hospital Mortality in Pediatric Postprocedural Respiratory Complications.Healthcare (Basel, Switzerland) · 2026Article
- Ventilation Intensity and Prognosis in Pediatric Oncology: Mechanical Power, Compliance, and Mortality Risk.Pediatric pulmonology · 2026Observational
- Age-related differences and common pathways of lymphocyte subsets in sepsis: a comparative review of elderly and pediatric patients.Cell death & disease · 2026Review
- End-of-life circumstances and unanticipated deaths in a neonatal intensive care unit: a retrospective analysis.BMC palliative care · 2026Article
- Acute gastrointestinal injury severity assessment informs nutritional support and prognostic evaluation in critically ill children: a narrative review.Frontiers in nutrition · 2026Review
- Evaluation of extracorporeal membrane oxygenation in children with acute hypoxemic respiratory failure and hemodynamic instability in China: a 7-year single-center retrospective study.Frontiers in medicine · 2026Article
- An interpretable machine learning model with SHAP explanations predicts spontaneous bleeding in pediatric acute liver failure.Frontiers in medicine · 2026Article
- Multiple organ dysfunction syndrome in pediatric colchicine poisoning: a national cohort study from Türkiye.Turkish journal of medical sciences · 2026Article
- Role of Hemoperfusion With HA330 in the Management of Severe Dengue Shock Syndrome.Journal of tropical medicine · 2026Article
- Prognostic value of cardiac biomarkers and Phoenix criteria in pediatric sepsis: a retrospective cohort study.BMC pediatrics · 2025Article
- The PICU Data Collaborative: A Novel, Multi-Institutional, Pediatric Critical Care Dataset.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2025Article
- Phoenix Sepsis Criteria in Critically Ill Children: Retrospective Validation Using a United States Nine-Center Dataset, 2012-2018.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2025Article
- Functional echocardiography identifies association between early ventricular dysfunction and outcome in pediatric sepsis.Frontiers in pediatrics · 2025Article
- NeutrophilFrontiers in cardiovascular medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
84 authors at 20 institutions in 3 countries.
Melania M BembeaDepartment of Anesthesiology and Critical Care Medicine.
Michael AgusDivision of Medical Critical Care.
Ayse Akcan-ArikanSections of Critical Care and Nephrology.
Peta AlexanderDepartment of Cardiology.
Rajit BasuDivision of Pediatric Critical Care, Children's Healthcare of Atlanta.
Tellen D BennettSections of Informatics and Data Science and Critical Care Medicine, Department of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, Colorado.
Desmond BohnDepartment of Critical Care Medicine.
Leonardo R BrandãoDivision of Hematology-Oncology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Toronto, Ontario, Canada.
Ann-Marie BrownNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia.
Joseph A CarcilloDivision of Pediatric Critical Care Medicine, Department of Critical Care Medicine, University of Pittsburgh School of Medicine.
Paul ChecchiaSection of Critical Care Medicine, Department of Pediatrics, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas.
Jill CholetteDepartment of Pediatrics, University of Rochester Golisano Children's Hospital, Rochester, New York.
Ira M CheifetzDepartment of Pediatrics, Rainbow Babies and Children's Hospital, Case Western Reserve University School of Medicine, Cleveland, Ohio.
Timothy CornellDivision of Pediatric Critical Care Medicine, Department of Pediatrics, Stanford University School of Medicine, Lucile Packard Children's Hospital Stanford, Palo Alto, California.
Allan DoctorCenter for Blood Oxygen Transport and Hemostasis, University of Maryland School of Medicine, Baltimore, Maryland.
Michelle EckerleDepartment of Pediatrics, University of Cincinnati College of Medicine.
Simon EricksonDepartment of Paediatric Critical Care; Perth Children's Hospital and University of Western Australia, Perth, Western Australia, Australia.
Reid W D FarrisDepartment of Pediatrics, Seattle Children's Hospital, University of Washington Seattle, Washington.
E Vincent S FaustinoSection of Pediatric Critical Care Medicine, Department of Pediatrics, Yale School of Medicine, New Haven, Connecticut.
Julie C FitzgeraldDepartment of Anesthesiology and Critical Care, The University of Pennsylvania Perelman School of Medicine and Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Dana Y FuhrmanDivision of Pediatric Critical Care Medicine, Department of Critical Care Medicine, University of Pittsburgh School of Medicine.
John S GiulianoSection of Pediatric Critical Care Medicine, Department of Pediatrics, Yale School of Medicine, New Haven, Connecticut.
Kristin GuilliamsDivision of Pediatric and Development Neurology, Department of Neurology, and Division of Pediatric Critical Care Medicine.
Michael GaiesDepartment of Pediatrics, University of Michigan, Ann Arbor, Michigan.
Stephen M GorgaDepartment of Pediatrics, University of Michigan, Ann Arbor, Michigan.
Mark HallDivision of Critical Care Medicine, Department of Pediatrics, The Ohio State University College of Medicine, Nationwide Children's Hospital, Columbus, Ohio.
Sheila J HansonCritical Care Section, Department of Pediatrics, Medical College of Wisconsin/Children's Wisconsin, Milwaukee, Wisconsin.
Mary HartmanDepartment of Anesthesiology and Critical Care Medicine.
Amanda B HassingerDivision of Medical Critical Care.
Sharon Y IrvingSections of Critical Care and Nephrology.
Howard JeffriesDepartment of Pediatrics, Seattle Children's Hospital, University of Washington Seattle, Washington.
Philippe JouvetDepartment of Cardiology.
Sujatha KannanDepartment of Anesthesiology and Critical Care Medicine.
Oliver KaramDepartment of Pediatrics, Boston Children's Hospital.
Robinder G KhemaniDivision of Pediatric Critical Care, Children's Healthcare of Atlanta.
Niranjan KissoonSections of Informatics and Data Science and Critical Care Medicine, Department of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, Colorado.
Jacques LacroixDepartment of Critical Care Medicine.
Peter LaussenDepartment of Cardiology.
Francis LeclercNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia.
Jan Hau LeeDivision of Pediatric Critical Care Medicine, Department of Critical Care Medicine, University of Pittsburgh School of Medicine.
Stephane LeteurtreNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia.
Katie LobnerSection of Critical Care Medicine, Department of Pediatrics, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas.
Patrick J McKiernanDepartment of Pediatrics, University of Rochester Golisano Children's Hospital, Rochester, New York.
Kusum MenonDepartment of Pediatrics, Rainbow Babies and Children's Hospital, Case Western Reserve University School of Medicine, Cleveland, Ohio.
Paul MonagleDivision of Pediatric Critical Care Medicine, Department of Pediatrics, Stanford University School of Medicine, Lucile Packard Children's Hospital Stanford, Palo Alto, California.
Jennifer A MuszynskiDivision of Critical Care Medicine, Department of Pediatrics, The Ohio State University College of Medicine, Nationwide Children's Hospital, Columbus, Ohio.
Folafoluwa OdetolaDepartment of Pediatrics, University of Michigan, Ann Arbor, Michigan.
Robert ParkerCenter for Blood Oxygen Transport and Hemostasis, University of Maryland School of Medicine, Baltimore, Maryland.
Nazima PathanDepartment of Pediatrics, University of Cincinnati College of Medicine.
Richard W PierceSection of Pediatric Critical Care Medicine, Department of Pediatrics, Yale School of Medicine, New Haven, Connecticut.
Jose PinedaDivision of Pediatric Critical Care, Children's Healthcare of Atlanta.
Jose M PrinceDivision of Emergency Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Karen A RobinsonDepartment of Paediatric Critical Care; Perth Children's Hospital and University of Western Australia, Perth, Western Australia, Australia.
Courtney M RowanDepartment of Pediatrics, Seattle Children's Hospital, University of Washington Seattle, Washington.
Lindsay M RyersonSection of Pediatric Critical Care Medicine, Department of Pediatrics, Yale School of Medicine, New Haven, Connecticut.
L Nelson Sanchez-PintoDepartment of Anesthesiology and Critical Care, The University of Pennsylvania Perelman School of Medicine and Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Luregn J SchlapbachDivision of Pediatric and Development Neurology, Department of Neurology, and Division of Pediatric Critical Care Medicine.
David T SelewskiDepartment of Pediatrics, University of Michigan, Ann Arbor, Michigan.
Lara S ShekerdemianSection of Critical Care Medicine, Department of Pediatrics, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas.
Dennis SimonDivision of Pediatric Critical Care Medicine, Department of Critical Care Medicine, University of Pittsburgh School of Medicine.
Lincoln S SmithDepartment of Pediatrics, Seattle Children's Hospital, University of Washington Seattle, Washington.
James E SquiresDepartment of Pediatrics, University of Rochester Golisano Children's Hospital, Rochester, New York.
Robert H SquiresDepartment of Pediatrics, University of Rochester Golisano Children's Hospital, Rochester, New York.
Scott M SutherlandDivision of Critical Care Medicine, Department of Pediatrics, The Ohio State University College of Medicine, Nationwide Children's Hospital, Columbus, Ohio.
Yves OuelletteCritical Care Section, Department of Pediatrics, Medical College of Wisconsin/Children's Wisconsin, Milwaukee, Wisconsin.
Michael C SpaederDepartment of Anesthesiology and Critical Care Medicine.
Vijay SrinivasanDepartment of Anesthesiology and Critical Care, The University of Pennsylvania Perelman School of Medicine and Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Marie E SteinerDivision of Medical Critical Care.
Robert C TaskerDivision of Hematology-Oncology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Toronto, Ontario, Canada.
Ravi ThiagarajanDepartment of Cardiology.
Neal ThomasSections of Critical Care and Nephrology.
Pierre TissieresDepartment of Cardiology.
Chani TraubeDepartment of Pediatrics, Boston Children's Hospital.
Marisa TucciDepartment of Critical Care Medicine.
Katri V TyppoDivision of Pediatric Critical Care, Children's Healthcare of Atlanta.
Mark S WainwrightSections of Informatics and Data Science and Critical Care Medicine, Department of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, Colorado.
Shan L WardDepartment of Critical Care Medicine.
R Scott WatsonDepartment of Pediatrics, Seattle Children's Hospital, University of Washington Seattle, Washington.
Scott WeissDepartment of Anesthesiology and Critical Care, The University of Pennsylvania Perelman School of Medicine and Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Jane WhitneyDivision of Medical Critical Care.
Doug WillsonDepartment of Pediatrics, Boston Children's Hospital.
James L WynnDivision of Hematology-Oncology, Department of Paediatrics, University of Toronto, The Hospital for Sick Children, Toronto, Ontario, Canada.
Nadir YehyaDepartment of Anesthesiology and Critical Care, The University of Pennsylvania Perelman School of Medicine and Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Jerry J ZimmermanDepartment of Pediatrics, Seattle Children's Hospital, University of Washington Seattle, Washington.
Boston Children's Hospital · USChildren's Healthcare of Atlanta · USUniversity of Michigan–Ann Arbor · USUniversity of Pittsburgh · USUniversity of Washington · USYale University · USEmory University · USUniversity of Pennsylvania · USUniversity of Rochester · USChildren's Hospital Colorado · USChildren's Hospital of Philadelphia · USChildren's Hospital of Wisconsin · USHospital for Sick Children · CANationwide Children's Hospital · USSeattle Children's Hospital · USTexas Children's Hospital · USUniversity of Cincinnati Medical Center · USUniversity of Maryland, Baltimore · USUniversity of Toronto · CABaylor College of Medicine · US
Funding
Biomarkers of Brain Injury in Critically-Ill Children on Extracorporeal Membrane Oxygenation (ECMO)R01NS106292 · NINDS · JOHNS HOPKINS UNIVERSITY · PI BEMBEA, MELANIA MARIA · 2019 to 2023
$3.1MNINDS NIH HHS R01 NS106292
Abstract
Prior criteria for organ dysfunction in critically ill children were based mainly on expert opinion. We convened the Pediatric Organ Dysfunction Information Update Mandate (PODIUM) expert panel to summarize data characterizing single and multiple organ dysfunction and to derive contemporary criteria for pediatric organ dysfunction. The panel was composed of 88 members representing 47 institutions and 7 countries. We conducted systematic reviews of the literature to derive evidence-based criteria for single organ dysfunction for neurologic, cardiovascular, respiratory, gastrointestinal, acute liver, renal, hematologic, coagulation, endocrine, endothelial, and immune system dysfunction. We searched PubMed and Embase from January 1992 to January 2020. Study identification was accomplished using a combination of medical subject headings terms and keywords related to concepts of pediatric organ dysfunction. Electronic searches were performed by medical librarians. Studies were eligible for inclusion if the authors reported original data collected in critically ill children; evaluated performance characteristics of scoring tools or clinical assessments for organ dysfunction; and assessed a patient-centered, clinically meaningful outcome. Data were abstracted from each included study into an electronic data extraction form. Risk of bias was assessed using the Quality in Prognosis Studies tool. Consensus was achieved for a final set of 43 criteria for pediatric organ dysfunction through iterative voting and discussion. Although the PODIUM criteria for organ dysfunction were limited by available evidence and will require validation, they provide a contemporary foundation for researchers to identify and study single and multiple organ dysfunction in critically ill children.
Indexed as
Organ Dysfunction ScoresChildCritical CareCritical IllnessEvidence-Based MedicineHumansMultiple Organ Failure
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.