Evidence map›Paper›PMID 34970488›Full record

ArticleFrontiers in oncology2021

Retrospective Review of Flexible Bronchoscopy in Pediatric Cancer Patients.

Ali H Ahmad, Brandon D Brown, Clark R Andersen, Kris M Mahadeo, Demetrios Petropolous, José A Cortes, Shehla Razvi, Mary Katherine Gardner, Linette J Ewing, Rodrigo E Mejia

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Ali H AhmadPediatric Critical Care Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Brandon D BrownPediatric Oncology Fellowship Program, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Clark R AndersenBiostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Kris M MahadeoPediatric Stem Cell Transplantation and Cellular Therapy and CARTOX Program, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Demetrios PetropolousPediatric Stem Cell Transplantation and Cellular Therapy and CARTOX Program, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
José A CortesPediatric Critical Care Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Shehla RazviPediatric Critical Care Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Mary Katherine GardnerPediatric Critical Care Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Linette J EwingPediatric Critical Care Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
Rodrigo E MejiaPediatric Critical Care Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.
The University of Texas MD Anderson Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of flexible bronchoscopy (FB) with bronchoalveolar lavage (BAL) to diagnose and manage pulmonary complications has been shown to be safe in adult cancer patients, but whether its use is safe in pediatric cancer patients remains unclear. Thus, to describe the landscape of FB outcomes in pediatric cancer patients and to help define the populations most likely to benefit from the procedure, we undertook a retrospective review of FBs performed in patients younger than 21 years treated at our institution from 2002 to 2017. We found that a greater volume of total fluid instilled during BAL was significantly associated with increased probabilities of positive BAL culture (p=0.042), positive bacterial BAL culture (p=0.037), and positive viral BAL culture (p=0.0496). In more than half of the FB cases, findings resulted in alterations in antimicrobial treatment. Our study suggests that for pediatric cancer patients, FB is safe, likely provides diagnostic and/or therapeutic benefits, and has implications for treatment decisions.

Indexed as

BALbronchoscopypediatric cancerpediatric critical carepediatric oncology

Identifiers

PMID34970488
PMCPMC8712312
OpenAlexW4200025714

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.