Evidence map›Paper›PMID 34970471›Full record

ArticleThe Journal of innovations in cardiac rhythm management2021

Treatment of Cryptogenic Stroke Patients with Atrial Fibrillation Detected by Insertable Cardiac Monitors Reduces Recurrent Stroke Risk to Background Levels.

E Martin Kloosterman, Jonathan Z Rosman, Eric J Berkowitz, Murray Rosenbaum, Zachary A Wettenstein

Open access · diamondAbstract read
In one paragraph

Article in The Journal of innovations in cardiac rhythm management, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Observational
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

E Martin KloostermanCardiac Arrhythmia Services, Florida Atlantic University CESCOM, Boca Raton, FL, USA.
Jonathan Z RosmanCardiac Arrhythmia Services, Florida Atlantic University CESCOM, Boca Raton, FL, USA.
Eric J BerkowitzCardiac Arrhythmia Services, Florida Atlantic University CESCOM, Boca Raton, FL, USA.
Murray RosenbaumCardiac Arrhythmia Services, Florida Atlantic University CESCOM, Boca Raton, FL, USA.
Zachary A WettensteinCardiac Arrhythmia Services, Florida Atlantic University CESCOM, Boca Raton, FL, USA.
Florida Atlantic University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atrial fibrillation (AF) is a known risk factor of ischemic stroke with a reported fivefold increase in incidence. However, it is not well established whether treatment with oral anticoagulation (OAC) in cryptogenic stroke patients with AF, detected by insertable cardiac monitors (ICMs), reduces the risk of recurrent stroke. We aimed to compare recurrent stroke rates between cryptogenic stroke patients who have AF detected by ICMs and thus started on OAC treatment and those without detected AF. We performed a combined retrospective and prospective analysis of consecutive patients who received an ICM indicated for cryptogenic stroke and were followed up with between July 2015 and November 2019. Patients with a prior documented history of AF were excluded. All patients were required to have a home remote monitoring system. We calculated the rates of AF detection and OAC initiation, then compared recurrent annualized stroke rates (ASRs) between patients with and without AF detected. A total of 298 patients with ICMs were included in the study [mean ± standard deviation age: 77 ± 11.7 years; female/male: 147/151; virtual CHA

Indexed as

Atrial fibrillationcryptogenic strokeguided oral anticoagulation therapyimplantable cardiac monitorstroke reduction

Identifiers

PMID34970471
PMCPMC8711968
OpenAlexW4226190919

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.