Evidence map›Paper›PMID 34970429›Full record

ArticleFrontline gastroenterology2022

Recent advances in liver transplantation.

N Thomas Burke, James B Maurice, David Nasralla, Jonathan Potts, Rachel Westbrook

Abstract read
In one paragraph

Article in Frontline gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Management of liver diseases: Current perspectives.World journal of gastroenterology · 2022
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

N Thomas Burke *Hepatology and Liver Transplantation, Royal Free London NHS Foundation Trust, London, London, UK.
James B Maurice *Hepatology and Liver Transplantation, Royal Free London NHS Foundation Trust, London, London, UK.ORCID 0000-0003-1530-5328
David NasrallaHepatobiliary Surgery, Royal Free London NHS Foundation Trust, London, London, UK.
Jonathan PottsHepatology and Liver Transplantation, Royal Free London NHS Foundation Trust, London, London, UK.
Rachel WestbrookHepatology and Liver Transplantation, Royal Free London NHS Foundation Trust, London, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver transplant is a life-saving treatment with 1-year and 5-year survival rates of 90% and 70%, respectively. However, organ demand continues to exceed supply, such that many patients will die waiting for an available organ. This article reviews for the general gastroenterologist the latest developments in the field to reduce waiting list mortality and maximise utilisation of available organs. The main areas covered include legislative changes in organ donation and the new 'opt-out' systems being rolled out in the UK, normothermic machine perfusion to optimise marginal grafts, a new national allocation system to maximise benefit from each organ and developments in patient 'prehabilitation' before listing. Current areas of research interest, such as immunosuppression withdrawal, are also summarised.

Indexed as

liver transplantation

Identifiers

PMID34970429
PMCPMC8666869

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.