Evidence map›Paper›PMID 34970396›Full record

ArticleThe Pan African medical journal2021

Kearns Sayre syndrome: a rare etiology of complete atrioventricular block in children (case report).

Hanane Kharbouch, Badr Boussaadani, Ibtissam Fellat, Latifa Oukerraj, Nawal Doghmi, Mohamed Cherti

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The Pan African medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hanane KharbouchCardiovascular Diseases B Department, Ibn Sina Medical Hospital, Mohamed V University, Rabat, Morocco.
Badr BoussaadaniCardiovascular Diseases B Department, Ibn Sina Medical Hospital, Mohamed V University, Rabat, Morocco.
Ibtissam FellatCardiovascular Diseases B Department, Ibn Sina Medical Hospital, Mohamed V University, Rabat, Morocco.
Latifa OukerrajCardiovascular Diseases B Department, Ibn Sina Medical Hospital, Mohamed V University, Rabat, Morocco.
Nawal DoghmiCardiovascular Diseases B Department, Ibn Sina Medical Hospital, Mohamed V University, Rabat, Morocco.
Mohamed ChertiCardiovascular Diseases B Department, Ibn Sina Medical Hospital, Mohamed V University, Rabat, Morocco.
Ibn Sina Hospital · KW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kearns Sayre syndrome is a rare mitochondrial abnormality first described in 1958, characterized by a triad associating progressive external ophthalmoplegia, ptosis, and pigmentary retinopathy with progressive alteration of cardiac conduction, which determines the vital prognosis of this entity. Here we report the case of a 13-year-old child of consanguineous parents who consults for recurrent syncope. The clinical exam found bilateral ptosis with complete atrioventricular block on electrocardiogram. The ophthalmological exam found pigmentary retinopathy. The patient underwent successful implantation of a double chamber pacemaker within 24 hours of admission, with an uneventful postoperative course. This case report highlights the interest of systematically assessing cardiac complications in children with mitochondrial disease such as Kearns Sayre syndrome, especially since cardiac involvement is the major prognostic factor in this disease.

Indexed as

Atrioventricular BlockBlepharoptosisKearns-Sayre SyndromePacemaker, ArtificialAdolescentChildElectrocardiographyHumansatrioventricular blockcase reportimplantable automatic defibrillatorKearns Sayre syndromepeacemaker implantation

Identifiers

PMID34970396
PMCPMC8683484
OpenAlexW3214759921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.