Evidence map›Paper›PMID 34970257›Full record

ArticleFrontiers in immunology2021

CD8

Xiangkun Wu, Dongmei Jiang, Hongling Liu, Xiaofan Lu, Daojun Lv, Li Liang

Abstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Interferon Epsilon Loss Is Elusive 9p21 Link to Immune-Cold Tumors, Resistant to Immune Checkpoint Therapy, and Endogenous CXCL9/10 Induction.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiangkun WuDepartment of Pathology, Nanfang Hospital and Basic Medical College, Southern Medical University, Guangzhou, China.
Dongmei JiangDepartment of Pathology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Hongling LiuDepartment of Pathology, Nanfang Hospital and Basic Medical College, Southern Medical University, Guangzhou, China.
Xiaofan LuState Key Laboratory of Natural Medicines, Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, Nanjing, China.
Daojun LvDepartment of Urology, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Li LiangDepartment of Pathology, Nanfang Hospital and Basic Medical College, Southern Medical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The tumor microenvironment (TME) exerts a high impact on tumor biology and immunotherapy. The heterogeneous phenotypes and the clinical significance of CD8

Indexed as

Biomarkers, TumorCarcinoma, Renal CellCD8-Positive T-LymphocytesHumansKidney NeoplasmsTumor MicroenvironmentBiomarkers, TumorCD8+ T cellsclear cell renal cell carcinomaimmune checkpoint blockade therapyimmunogenomic analysisunsupervised cluster analysis

Identifiers

PMID34970257
PMCPMC8713701

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.