Evidence map›Paper›PMID 34970170›Full record

ArticleFrontiers in psychiatry2021

Atypical Resting State Functional Neural Network in Children With Autism Spectrum Disorder: Graph Theory Approach.

Daiki Soma, Tetsu Hirosawa, Chiaki Hasegawa, Kyung-Min An, Masafumi Kameya, Shoryoku Hino, Yuko Yoshimura, Sou Nobukawa, Sumie Iwasaki, Sanae Tanaka and 5 more

Abstract read
In one paragraph

Article in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Daiki SomaDepartment of Psychiatry and Neurobiology, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.
Tetsu HirosawaDepartment of Psychiatry and Neurobiology, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.
Chiaki HasegawaResearch Center for Child Mental Development, Kanazawa University, Kanazawa, Japan.
Kyung-Min AnResearch Center for Child Mental Development, Kanazawa University, Kanazawa, Japan.
Masafumi KameyaDepartment of Psychiatry and Neurobiology, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.
Shoryoku HinoDepartment of Neuropsychiatry, Ishikawa Prefectural Takamatsu Hospital, Kahoku, Japan.
Yuko YoshimuraResearch Center for Child Mental Development, Kanazawa University, Kanazawa, Japan.
Sou NobukawaDepartment of Computer Science, Chiba Institute of Technology, Narashino, Japan.
Sumie IwasakiResearch Center for Child Mental Development, Kanazawa University, Kanazawa, Japan.
Sanae TanakaResearch Center for Child Mental Development, Kanazawa University, Kanazawa, Japan.
Ken YaoiResearch Center for Child Mental Development, Kanazawa University, Kanazawa, Japan.
Masuhiko SanoDepartment of Psychiatry and Neurobiology, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.
Yuka ShiotaResearch Center for Child Mental Development, Kanazawa University, Kanazawa, Japan.
Nobushige NaitoDepartment of Psychiatry and Neurobiology, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.
Mitsuru KikuchiDepartment of Psychiatry and Neurobiology, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Measuring whole brain networks is a promising approach to extract features of autism spectrum disorder (ASD), a brain disorder of widespread regions. Objectives of this study were to evaluate properties of resting-state functional brain networks in children with and without ASD and to evaluate their relation with social impairment severity. Magnetoencephalographic (MEG) data were recorded for 21 children with ASD (7 girls, 60-89 months old) and for 25 typically developing (TD) control children (10 girls, 60-91 months old) in a resting state while gazing at a fixation cross. After signal sources were localized onto the Desikan-Killiany brain atlas, statistical relations between localized activities were found and evaluated in terms of the phase lag index. After brain networks were constructed and after matching with intelligence using a coarsened exact matching algorithm, ASD and TD graph theoretical measures were compared. We measured autism symptoms severity using the Social Responsiveness Scale and investigated its relation with altered small-worldness using linear regression models. Children with ASD were found to have significantly lower small-worldness in the beta band (

Indexed as

autismgraph theoryMEGsmall-worldnesssocial communication

Identifiers

PMID34970170
PMCPMC8712628

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.