Evidence map›Paper›PMID 34970032›Full record

ArticleProceedings (Baylor University. Medical Center)2022

Meta-analysis of randomized controlled trials on primary ambulatory thromboprophylaxis in patients with nonpancreatic gastrointestinal cancers receiving chemotherapy.

Thura Win Htut, Kyaw Zin Thein, Donald Paul Quick, Thein Hlaing Oo

Open access · greenAbstract read
In one paragraph

Article in Proceedings (Baylor University. Medical Center), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Thura Win HtutDepartment of Hematology, Aberdeen Royal Infirmary, Aberdeen, UK.ORCID https://orcid.org/0000-0002-5508-1472
Kyaw Zin TheinDepartment of Investigational Cancer Therapeutics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas.ORCID https://orcid.org/0000-0003-1518-1097
Donald Paul QuickJoe Arrington Cancer Research and Treatment Center, Lubbock, Texas.
Thein Hlaing OoSection of Benign Hematology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas.ORCID https://orcid.org/0000-0002-5201-731X
The University of Texas MD Anderson Cancer Center · USAberdeen Royal Infirmary · GBTexas Tech University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary ambulatory thromboprophylaxis (PATP) in patients with solid malignancies is not routinely indicated. We performed a meta-analysis of randomized controlled trials (RCTs) to determine the benefit and risk of PATP in patients with nonpancreatic gastrointestinal cancers receiving chemotherapy. RCTs with venous thromboembolism (VTE) reduction as primary or secondary endpoints were included. A total of 1932 patients from subgroups of 3 RCTs were eligible. The VTE incidence was 1.26% and 2.55% in PATP and control arms, respectively (risk ratio 0.49; confidence interval 0.25 to 0.96;

Indexed as

Ambulatory thromboprophylaxiscolorectal cancergastric cancergastroesophageal junctional cancermeta-analysisvenous thromboembolism

Identifiers

PMID34970032
PMCPMC8682846
OpenAlexW3200420363

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.