Evidence map›Paper›PMID 34970013›Full record

ArticleTetrahedron letters2021

Sequential iodine-mediated diallylsilane rearrangement/asymmetric dihydroxylation: Synthesis and reactions of enantioenriched oxasilacycles.

Christopher R Myers, Paul Spaltenstein, Lauren K Baker, Cody L Schwans, Timothy B Clark, Gregory W O'Neil

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tetrahedron letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Christopher R MyersDepartment of Chemistry, Western Washington University, Bellingham, WA, 98225, USA.
Paul SpaltensteinDepartment of Chemistry, Western Washington University, Bellingham, WA, 98225, USA.
Lauren K BakerDepartment of Chemistry, Western Washington University, Bellingham, WA, 98225, USA.
Cody L SchwansDepartment of Chemistry, Western Washington University, Bellingham, WA, 98225, USA.
Timothy B ClarkDepartment of Chemistry, University of San Diego, San Diego, CA, 92110, USA.
Gregory W O'NeilDepartment of Chemistry, Western Washington University, Bellingham, WA, 98225, USA.
Western Washington University · USUniversity of San Diego · US

Funding

Nucleophilic borylation of aldehydes and conjugated carbonyls: Applications to homologation and carbosilylation reactionsR15GM119034 · NIGMS · UNIVERSITY OF SAN DIEGO · PI CLARK, TIMOTHY B, O'NEIL, GREGORY W · 2016 to 2016
$380k
NIGMS NIH HHS R15 GM119034
6 · The paper itself

Abstract

Products from an iodine-mediated diallylsilane rearrangement were taken into an asymmetric dihydroxylation (AD) reaction resulting in the formation of diastereomeric 6-membered oxasilacycles. Removal of the epimeric stereocenter among this mixture of diastereomers by elimination of iodine produced a single enantioenriched cyclic allyl silyl ether. The resulting allyl silane was then successfully engaged in several further transformations, providing an alternative means to prepare useful intermediates for enantioselective synthesis.

Indexed as

AllylsilaneAsymmetric DihydroxylationDiallylsilaneOxasilacycleRearrangement

Identifiers

PMID34970013
PMCPMC8714181
OpenAlexW3197196132

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.