Evidence map›Paper›PMID 34969852›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Sod1 integrates oxygen availability to redox regulate NADPH production and the thiol redoxome.

Claudia Montllor-Albalate, Hyojung Kim, Anna E Thompson, Alex P Jonke, Matthew P Torres, Amit R Reddi

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
4.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 79 citations in OpenAlex.

  1. The toxic footprint of lead exposure: oxido-inflammatory biomarkers in urban populations of Niger Delta, Nigeria.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
  2. Cascading damage toProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. Disulfide-Bridged Ru Complex-Mediated Photo-Disulfidptosis for Colorectal Cancer Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Claudia Montllor-AlbalateSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332.ORCID 0000-0003-0001-0236
Hyojung KimSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332.
Anna E ThompsonSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332.
Alex P JonkeSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332.
Matthew P TorresSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332; mtorres35@gatech.edu amit.reddi@chemistry.gatech.edu.ORCID 0000-0001-7296-4536
Amit R ReddiSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332; mtorres35@gatech.edu amit.reddi@chemistry.gatech.edu.
Georgia Institute of Technology · US

Funding

The Role of Cu/Zn Superoxide Dismutase (SOD1) in Redox SignalingR01GM118744 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI REDDI, AMIT RAM · 2016 to 2020
$1.6M
NIGMS NIH HHS R01 GM118744
6 · The paper itself

Abstract

Cu/Zn superoxide dismutase (Sod1) is a highly conserved and abundant antioxidant enzyme that detoxifies superoxide (O

Indexed as

AnimalsAntioxidantsGlycolysisHydrogen PeroxideNADPOxidation-ReductionOxygenReactive Oxygen SpeciesSaccharomyces cerevisiaeSignal TransductionSulfhydryl CompoundsSuperoxide DismutaseSuperoxide Dismutase-1SuperoxidesAntioxidantsHydrogen PeroxideNADPOxygenReactive Oxygen SpeciesSulfhydryl CompoundsSuperoxide DismutaseSuperoxide Dismutase-1Superoxidesglycolysisoxygen sensingpentose phosphate pathwayredox signalingsuperoxide dismutase

Identifiers

PMID34969852
PMCPMC8740578
OpenAlexW4225501713

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.