Evidence map›Paper›PMID 34969841›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Microstratigraphic preservation of ancient faunal and hominin DNA in Pleistocene cave sediments.

Diyendo Massilani, Mike W Morley, Susan M Mentzer, Vera Aldeias, Benjamin Vernot, Christopher Miller, Mareike Stahlschmidt, Maxim B Kozlikin, Michael V Shunkov, Anatoly P Derevianko and 13 more

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 91 citations in OpenAlex.

  1. Ancient DNA and Human Physiology.Physiology (Bethesda, Md.) · 2026
    Review
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  7. A high-coverage Neandertal genome from the Altai Mountains reveals population structure among Neandertals.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  8. Article
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  13. Archaic hominin admixture and its consequences for modern humans.Current opinion in genetics & development · 2025
    Review
  14. Article
  15. Review
  16. Sediment DNA can revolutionize archaeology-if it is used the right way.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 10 institutions in 8 countries.

Diyendo MassilaniDepartment of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, D-04103 Leipzig, Germany; paabo@eva.mpg.de diyendo_massilani@eva.mpg.de mmeyer@eva.mpg.de mike.morley@flinders.edu.au.ORCID 0000-0003-2661-4468
Mike W MorleyArchaeology, College of Humanities, Arts and Social Sciences, Flinders University, Adelaide, South Australia 5042, Australia; paabo@eva.mpg.de diyendo_massilani@eva.mpg.de mmeyer@eva.mpg.de mike.morley@flinders.edu.au.ORCID 0000-0001-7730-9637
Susan M MentzerInstitute for Archaeological Sciences, Eberhard Karls University of Tübingen, Tübingen, 72074 Tübingen, Germany.
Vera AldeiasInterdisciplinary Center for Archaeology and Evolution of Human Behaviour, University of Algarve, 8005-139 Faro, Portugal.ORCID 0000-0002-7680-182X
Benjamin VernotDepartment of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, D-04103 Leipzig, Germany.ORCID 0000-0002-6820-2181
Christopher MillerInstitute for Archaeological Sciences, Eberhard Karls University of Tübingen, Tübingen, 72074 Tübingen, Germany.
Mareike StahlschmidtDepartment of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Leipzig, D-04103 Leipzig, Germany.
Maxim B KozlikinInstitute of Archaeology and Ethnography, Russian Academy of Sciences, Siberian Branch, Novosibirsk 630090, Russia.ORCID 0000-0001-5082-3345
Michael V ShunkovInstitute of Archaeology and Ethnography, Russian Academy of Sciences, Siberian Branch, Novosibirsk 630090, Russia.ORCID 0000-0003-1388-2308
Anatoly P DereviankoInstitute of Archaeology and Ethnography, Russian Academy of Sciences, Siberian Branch, Novosibirsk 630090, Russia.ORCID 0000-0003-1156-8331
Nicholas J ConardInstitute for Archaeological Sciences, Eberhard Karls University of Tübingen, Tübingen, 72074 Tübingen, Germany.
Sarah WurzSentre For Fremragende Forskning (SFF), Centre for Early Sapiens Behaviour, University of Bergen, Bergen, 5020 Bergen, Norway.ORCID 0000-0002-0949-5391
Christopher S HenshilwoodSentre For Fremragende Forskning (SFF), Centre for Early Sapiens Behaviour, University of Bergen, Bergen, 5020 Bergen, Norway.ORCID 0000-0002-2818-293X
Javi VasquezCenter for Environmental Management of Military Lands, Colorado State University, Fort Collins, CO 80524.ORCID 0000-0002-0886-7894
Elena EsselDepartment of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, D-04103 Leipzig, Germany.ORCID 0000-0002-2642-8043
Sarah NagelDepartment of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, D-04103 Leipzig, Germany.
Julia RichterDepartment of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, D-04103 Leipzig, Germany.
Birgit NickelDepartment of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, D-04103 Leipzig, Germany.
Richard G RobertsCentre for Archaeological Science, School of Earth, Atmospheric and Life Sciences, University of Wollongong, Wollongong, New South Wales 2522, Australia.ORCID 0000-0002-0128-4119
Svante PääboDepartment of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, D-04103 Leipzig, Germany; paabo@eva.mpg.de diyendo_massilani@eva.mpg.de mmeyer@eva.mpg.de mike.morley@flinders.edu.au.ORCID 0000-0002-4670-6311
Viviane SlonDepartment of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, D-04103 Leipzig, Germany.ORCID 0000-0001-6485-7159
Paul GoldbergSenckenberg Centre for Human Evolution and Paleoenvironment, Universität Tübingen, Tübingen, 72070 Tübingen, Germany.ORCID 0000-0002-7059-1446
Matthias MeyerDepartment of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, D-04103 Leipzig, Germany; paabo@eva.mpg.de diyendo_massilani@eva.mpg.de mmeyer@eva.mpg.de mike.morley@flinders.edu.au.
Max Planck Institute for Evolutionary Anthropology · DEInstitute of Archaeology and Ethnography · RUSenckenberg Centre for Human Evolution and Palaeoenvironment · DEUniversity of the Witwatersrand · ZAAustralian Research Council · AUColorado State University · USFlinders University · AUTel Aviv University · ILUniversity of Algarve · PTUniversity of Wollongong · AU

Funding

COMPUTER AIDED ANALYSIS OF ELECTROCARDIOGRAPHYZ01CT000002 · CIT · COMPUTER RESEARCH AND TECHNOLOGY · PI BAILEY, JAMES J. · 1985 to 2003
–
Intramural NIH HHS Z01 CT000002
6 · The paper itself

Abstract

Ancient DNA recovered from Pleistocene sediments represents a rich resource for the study of past hominin and environmental diversity. However, little is known about how DNA is preserved in sediments and the extent to which it may be translocated between archaeological strata. Here, we investigate DNA preservation in 47 blocks of resin-impregnated archaeological sediment collected over the last four decades for micromorphological analyses at 13 prehistoric sites in Europe, Asia, Africa, and North America and show that such blocks can preserve DNA of hominins and other mammals. Extensive microsampling of sediment blocks from Denisova Cave in the Altai Mountains reveals that the taxonomic composition of mammalian DNA differs drastically at the millimeter-scale and that DNA is concentrated in small particles, especially in fragments of bone and feces (coprolites), suggesting that these are substantial sources of DNA in sediments. Three microsamples taken in close proximity in one of the blocks yielded Neanderthal DNA from at least two male individuals closely related to

Indexed as

CavesDNA, AncientFossilsAnimalsHominidaeNeanderthalsDNA, Ancientancient DNADenisova Cavesediment curationsediment DNAsoil micromorphology

Identifiers

PMID34969841
PMCPMC8740756
OpenAlexW4200146758

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.