Evidence map›Paper›PMID 34969678›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Modeling for COVID-19 college reopening decisions: Cornell, a case study.

Peter I Frazier, J Massey Cashore, Ning Duan, Shane G Henderson, Alyf Janmohamed, Brian Liu, David B Shmoys, Jiayue Wan, Yujia Zhang

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Optimal Adaptive Testing for Epidemic Control: Combining Molecular and Serology Tests.Automatica : the journal of IFAC, the International Federation of Automatic Control · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Early Introduction and Rise of the Omicron Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Variant in Highly Vaccinated University Populations.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Effect of mandating vaccination on COVID-19 cases in colleges and universities.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Peter I FrazierSchool of Operations Research & Information Engineering, Cornell University, Ithaca, NY 14850; pf98@cornell.edu.ORCID 0000-0002-3501-3341
J Massey CashoreSchool of Operations Research & Information Engineering, Cornell University, Ithaca, NY 14850.
Ning DuanSchool of Operations Research & Information Engineering, Cornell University, Ithaca, NY 14850.
Shane G HendersonSchool of Operations Research & Information Engineering, Cornell University, Ithaca, NY 14850.ORCID 0000-0003-1004-4034
Alyf JanmohamedSchool of Operations Research & Information Engineering, Cornell University, Ithaca, NY 14850.ORCID 0000-0003-0813-6503
Brian LiuSchool of Operations Research & Information Engineering, Cornell University, Ithaca, NY 14850.
David B ShmoysSchool of Operations Research & Information Engineering, Cornell University, Ithaca, NY 14850.ORCID 0000-0003-3882-901X
Jiayue WanSchool of Operations Research & Information Engineering, Cornell University, Ithaca, NY 14850.ORCID 0000-0002-8252-1584
Yujia ZhangCenter for Applied Mathematics, Cornell University, Ithaca, NY 14850.
Cornell University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We consider epidemiological modeling for the design of COVID-19 interventions in university populations, which have seen significant outbreaks during the pandemic. A central challenge is sensitivity of predictions to input parameters coupled with uncertainty about these parameters. Nearly 2 y into the pandemic, parameter uncertainty remains because of changes in vaccination efficacy, viral variants, and mask mandates, and because universities' unique characteristics hinder translation from the general population: a high fraction of young people, who have higher rates of asymptomatic infection and social contact, as well as an enhanced ability to implement behavioral and testing interventions. We describe an epidemiological model that formed the basis for Cornell University's decision to reopen for in-person instruction in fall 2020 and supported the design of an asymptomatic screening program instituted concurrently to prevent viral spread. We demonstrate how the structure of these decisions allowed risk to be minimized despite parameter uncertainty leading to an inability to make accurate point estimates and how this generalizes to other university settings. We find that once-per-week asymptomatic screening of vaccinated undergraduate students provides substantial value against the Delta variant, even if all students are vaccinated, and that more targeted testing of the most social vaccinated students provides further value.

Indexed as

Epidemiological ModelsAsymptomatic InfectionsCOVID-19Decision MakingHumansMass ScreeningReturn to SchoolSARS-CoV-2UncertaintyUnited StatesUniversitiesVaccinationasymptomatic screeningepidemiological modelingparameter uncertainty

Identifiers

PMID34969678
PMCPMC8764692
OpenAlexW4205965997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.