Evidence map›Paper›PMID 34969102›Full record

ReviewClinical chemistry2021

Evolving Applications of Artificial Intelligence and Machine Learning in Infectious Diseases Testing.

Nam K Tran, Samer Albahra, Larissa May, Sarah Waldman, Scott Crabtree, Scott Bainbridge, Hooman Rashidi

Abstract readReview
In one paragraph

Review in Clinical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nam K TranDepartment of Pathology and Laboratory Medicine, UC Davis School of Medicine, CA.
Samer AlbahraDepartment of Pathology and Laboratory Medicine, UC Davis School of Medicine, CA.
Larissa MayDepartment of Emergency Medicine, UC Davis School of Medicine, CA.
Sarah WaldmanDepartment of Internal Medicine, Division of Infectious Diseases, UC Davis School of Medicine, CA.
Scott CrabtreeDepartment of Internal Medicine, Division of Infectious Diseases, UC Davis School of Medicine, CA.
Scott BainbridgeDepartment of Pathology and Laboratory Medicine, UC Davis School of Medicine, CA.
Hooman RashidiDepartment of Pathology and Laboratory Medicine, UC Davis School of Medicine, CA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArtificial intelligence (AI) and machine learning (ML) are poised to transform infectious disease testing. Uniquely, infectious disease testing is technologically diverse spaces in laboratory medicine, where multiple platforms and approaches may be required to support clinical decision-making. Despite advances in laboratory informatics, the vast array of infectious disease data is constrained by human analytical limitations. Machine learning can exploit multiple data streams, including but not limited to laboratory information and overcome human limitations to provide physicians with predictive and actionable results. As a quickly evolving area of computer science, laboratory professionals should become aware of AI/ML applications for infectious disease testing as more platforms are become commercially available. CONTENT: In this review we: (a) define both AI/ML, (b) provide an overview of common ML approaches used in laboratory medicine, (c) describe the current AI/ML landscape as it relates infectious disease testing, and (d) discuss the future evolution AI/ML for infectious disease testing in both laboratory and point-of-care applications. SUMMARY: The review provides an important educational overview of AI/ML technique in the context of infectious disease testing. This includes supervised ML approaches, which are frequently used in laboratory medicine applications including infectious diseases, such as COVID-19, sepsis, hepatitis, malaria, meningitis, Lyme disease, and tuberculosis. We also apply the concept of "data fusion" describing the future of laboratory testing where multiple data streams are integrated by AI/ML to provide actionable clinical knowledge.

Indexed as

Artificial IntelligenceCommunicable DiseasesMachine LearningHumansCOVID-19data streamelectronic medical recordsimmunoassaysLyme diseasemeningitispoint-of-care testingpredictive analyticssensor fusionsepsistuberculosis

Identifiers

PMID34969102
PMCPMC9383167

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.