Evidence map›Paper›PMID 34968398›Full record

ArticlePloS one2021

COVID-19 associated hospitalization in 571 patients with fibromyalgia-A population-based study.

Mor Amital, Niv Ben-Shabat, Howard Amital, Dan Buskila, Arnon D Cohen, Daniela Amital

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mor AmitalThe Adelson School of Medicine, Ariel University, Ariel, Israel.
Niv Ben-ShabatDepartment of Medicine 'B' & Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel.
Howard AmitalThe Adelson School of Medicine, Ariel University, Ariel, Israel.ORCID 0000-0002-5406-7716
Dan BuskilaBen Gurion University of the Negev, Beer Sheva, Israel.
Arnon D CohenFaculty of Health Sciences, Siaal Research Center for Family Medicine and Primary Care, Beer Sheva, Israel.
Daniela AmitalBen Gurion University of the Negev, Beer Sheva, Israel.
Ben-Gurion University of the Negev · ILSheba Medical Center · ILTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify predicators of patients with fibromyalgia (FM) that are associated with a severe COVID-19 disease course.

methodsWe utilized the data base of the Clalit Health Services (CHS); the largest public organization in Israel, and extracted data concerning patients with FM. We matched two subjects without FM to each subject with FM by sex and age and geographic location. Baseline characteristics were evaluated by t-test for continuous variables and chi-square for categorical variables. Predictors of COVID-19 associated hospitalization were identified using univariable logistic regression model, significant variables were selected and analyzed by a multivariable logistic regression model.

resultsThe initial cohort comprised 18,598 patients with FM and 36,985 matched controls. The mean age was 57.5± 14.5(SD), with a female dominance of 91%. Out of this cohort we extracted the study population, which included all patients contracted with COVID-19, and consisted of 571 patients with FM and 1008 controls. By multivariable analysis, the following variables were found to predict COVID-19 associated hospitalization in patients with FM: older age (OR, 1.25; CI, 1.13-1.39; p<0.001), male sex (OR, 2.63; CI, 1.18-5.88; p<0.05) and hypertension (OR, 1.75; CI, 1.04-2.95; p<0.05).

conclusionThe current population-based study revealed that FM per se was not directly associated with COVID-19 hospitalization or related mortality. Yet classical risk factors endangering the general population were also relevant among patients with FM.

Indexed as

AdultAgedCOVID-19FemaleFibromyalgiaHospitalizationHumansIsraelMaleMiddle AgedRetrospective StudiesRisk FactorsSeverity of Illness Index

Identifiers

PMID34968398
PMCPMC8717981
OpenAlexW4200196548

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.