ArticlePLoS computational biology2021
When shared concept cells support associations: Theory of overlapping memory engrams.
Article in PLoS computational biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Hebb's Vision: The Structural Underpinnings of Hebbian Assemblies.bioRxiv : the preprint server for biology · 2025Article
- Input-driven dynamics for robust memory retrieval in Hopfield networks.Science advances · 2025Article
- A unified neural representation model for spatial and conceptual computations.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Formation and retrieval of cell assemblies in a biologically realistic spiking neural network model of area CA3 in the mouse hippocampus.Journal of computational neuroscience · 2024Article
- The Role of Intrinsic Plasticity in Engram Physiology and Temporal Memory Linking.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Review
- Engram mechanisms of memory linking and identity.Nature reviews. Neuroscience · 2024Review
- Intrinsic Neural Excitability Biases Allocation and Overlap of Memory Engrams.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Formation and Retrieval of Cell Assemblies in a Biologically Realistic Spiking Neural Network Model of Area CA3 in the Mouse Hippocampus.bioRxiv : the preprint server for biology · 2024Article
- Cortical cell assemblies and their underlying connectivity: An in silico study.PLoS computational biology · 2024Article
- Article
- Hippocampome.org v2.0: a knowledge base enabling data-driven spiking neural network simulations of rodent hippocampal circuits.bioRxiv : the preprint server for biology · 2024Article
- A Computational Framework for Memory Engrams.Advances in neurobiology · 2024Article
- Contextual memory engrams, and the neuromodulatory influence of the locus coeruleus.Frontiers in molecular neuroscience · 2024Review
- A dynamic attractor network model of memory formation, reinforcement and forgetting.PLoS computational biology · 2023Article
- Purely STDP-based assembly dynamics: Stability, learning, overlaps, drift and aging.PLoS computational biology · 2023Article
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5 authors.
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Abstract
Assemblies of neurons, called concepts cells, encode acquired concepts in human Medial Temporal Lobe. Those concept cells that are shared between two assemblies have been hypothesized to encode associations between concepts. Here we test this hypothesis in a computational model of attractor neural networks. We find that for concepts encoded in sparse neural assemblies there is a minimal fraction cmin of neurons shared between assemblies below which associations cannot be reliably implemented; and a maximal fraction cmax of shared neurons above which single concepts can no longer be retrieved. In the presence of a periodically modulated background signal, such as hippocampal oscillations, recall takes the form of association chains reminiscent of those postulated by theories of free recall of words. Predictions of an iterative overlap-generating model match experimental data on the number of concepts to which a neuron responds.
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