Evidence map›Paper›PMID 34968299›Full record

ArticleEpigenomes2021

The EpiDiverse Plant Epigenome-Wide Association Studies (EWAS) Pipeline.

Sultan Nilay Can, Adam Nunn, Dario Galanti, David Langenberger, Claude Becker, Katharina Volmer, Katrin Heer, Lars Opgenoorth, Noe Fernandez-Pozo, Stefan A Rensing

Abstract read
In one paragraph

Article in Epigenomes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sultan Nilay CanPlant Cell Biology, Department of Biology, University of Marburg, 35043 Marburg, Germany.
Adam NunnecSeq Bioinformatics GmbH, 04103 Leipzig, Germany.ORCID 0000-0002-9276-6243
Dario GalantiPlant Evolutionary Ecology, Institute of Evolution and Ecology, University of Tübingen, Auf der Morgenstelle 5, 72076 Tübingen, Germany.
David LangenbergerecSeq Bioinformatics GmbH, 04103 Leipzig, Germany.ORCID 0000-0001-9424-9701
Claude BeckerGregor Mendel Institute of Molecular Plant Biology (GMI), Austrian Academy of Sciences, Vienna BioCenter (VBC), Dr. Bohr-Gasse 3, 1030 Vienna, Austria.ORCID 0000-0003-3406-4670
Katharina VolmerDepartment of Forest Genetic Resources, Nordwestdeutsche Forstliche Versuchsanstalt (NW-FVA), 37079 Göttingen, Germany.
Katrin HeerConservation Biology, Department of Biology, University of Marburg, 35043 Marburg, Germany.ORCID 0000-0002-1036-599X
Lars OpgenoorthCentre for Biological Signaling Studies (BIOSS), University of Freiburg, 79104 Freiburg, Germany.
Noe Fernandez-PozoPlant Cell Biology, Department of Biology, University of Marburg, 35043 Marburg, Germany.ORCID 0000-0002-6489-5566
Stefan A RensingPlant Cell Biology, Department of Biology, University of Marburg, 35043 Marburg, Germany.

Funding

Deutsche Forschungsgemeinschaft HE 7345/2-1Horizon 2020 764965
6 · The paper itself

Abstract

Bisulfite sequencing is a widely used technique for determining DNA methylation and its relationship with epigenetics, genetics, and environmental parameters. Various techniques were implemented for epigenome-wide association studies (EWAS) to reveal meaningful associations; however, there are only very few plant studies available to date. Here, we developed the EpiDiverse EWAS pipeline and tested it using two plant datasets, from

Indexed as

DNA methylationEWASGWASnon-model speciespipelineplant epigenetics

Identifiers

PMID34968299
PMCPMC8594691

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.