Evidence map›Paper›PMID 34967504›Full record

Observational studyJournal of the International AIDS Society2021

Same-day antiretroviral therapy initiation hub model at the Thai Red Cross Anonymous Clinic in Bangkok, Thailand: an observational cohort study.

Pich Seekaew, Nittaya Phanuphak, Nipat Teeratakulpisarn, Sorawit Amatavete, Sita Lujintanon, Somsong Teeratakulpisarn, Tippawan Pankam, Oranuch Nampaisan, Pintip Jomja, Chotika Prabjunteuk and 3 more

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in Journal of the International AIDS Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04032028 (The Thai Red Cross AIDS Research Centre), which is not on this map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04032028 active not recruitingnot on this map

The Thai Red Cross AIDS Research Centre

TypeobservationalSponsorThai Red Cross AIDS Research CentreRan2018 to 2025Enrolled2,500ConditionsHIV Infections
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Pich SeekaewDepartment of Epidemiology, Columbia University Mailman School of Public Health, New York, New York, USA.ORCID 0000-0002-3941-3457
Nittaya PhanuphakInstitute of HIV Research and Innovation, Bangkok, Thailand.ORCID 0000-0002-0036-3165
Nipat TeeratakulpisarnInstitute of HIV Research and Innovation, Bangkok, Thailand.
Sorawit AmataveteInstitute of HIV Research and Innovation, Bangkok, Thailand.ORCID 0000-0002-1902-4016
Sita LujintanonInstitute of HIV Research and Innovation, Bangkok, Thailand.ORCID 0000-0001-5380-2013
Somsong TeeratakulpisarnThai Red Cross AIDS Research Centre, Bangkok, Thailand.
Tippawan PankamThai Red Cross AIDS Research Centre, Bangkok, Thailand.
Oranuch NampaisanInstitute of HIV Research and Innovation, Bangkok, Thailand.
Pintip JomjaThai Red Cross AIDS Research Centre, Bangkok, Thailand.
Chotika PrabjunteukInstitute of HIV Research and Innovation, Bangkok, Thailand.
Prapaipan PlodgratokeThai Red Cross AIDS Research Centre, Bangkok, Thailand.
Reshmie RamautarsingInstitute of HIV Research and Innovation, Bangkok, Thailand.ORCID 0000-0002-6293-9422
Praphan PhanuphakInstitute of HIV Research and Innovation, Bangkok, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWHO has recommended rapid antiretroviral therapy (ART) initiation, including same-day ART (SDART). However, data on the feasibility in real-world settings are limited. We implemented a cohort study at a stand-alone HIV testing centre to examine its applicability and effectiveness.

methodsData were collected from the Thai Red Cross Anonymous Clinic in Bangkok, Thailand, between July 2017 and July 2018 from clients who were ART-naïve and could return for follow-up visits. Baseline laboratory tests and chest X-ray were performed according to national guidelines, and clinical eligibility was determined based on physical examination and chest X-ray findings. Primary outcomes were retention in care and viral load suppression at 3, 6 and 12 months.

resultsDuring the study period, 2427 people tested HIV positive. Of these, 2107 (2207/2427, 86.8%) met logistical criteria, and 1904 (1904/2427, 78.5%) agreed to SDART. One thousand seven hundred and twenty-nine (1729/2427, 71.2%) were placed on ART, with 1257 received same-day initiation and 1576 initiated ART within 7 days; 1198 clients were successfully referred to free, sustained ART sites. Retention among eligible clients who accepted SDART service at months 3, 6 and 12 was 79.8%, 75.2% and 75.3%, respectively.

conclusionsSame-day ART initiation hub model at a stand-alone HIV testing centre in an urban setting in Bangkok, Thailand, is highly feasible and has a potential for scaling up. CLINICAL TRIAL NUMBER: NCT04032028.

Indexed as

Anti-HIV AgentsHIV InfectionsCohort StudiesHumansRed CrossThailandAnti-HIV Agentskey and vulnerable populationslinkage to careretentiontreatmentviral suppression

Identifiers

PMID34967504
PMCPMC8717692

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.