Trial reportJournal of the American Geriatrics Society2022
Sources of medication omissions among hospitalized older adults with polypharmacy.
Trial report in Journal of the American Geriatrics Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02979353 (A Randomized Controlled Trial to Deprescribe for Older Patients With Polypharmacy Transferred From the Hospital to Skilled Nursing Facilities), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Controlled Trial to Deprescribe for Older Patients With Polypharmacy Transferred From the Hospital to Skilled Nursing Facilities
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Medication Use Quality and Safety in Older Adults: 2023 Update.Journal of the American Geriatrics Society · 2025Pooled it
- Patient-Reported Barriers and Enablers to Deprescribing Recommendations During a Clinical Trial (Shed-MEDS).The Gerontologist · 2023Trial
- Deprescribing Medications Among Older Adults From End of Hospitalization Through Postacute Care: A Shed-MEDS Randomized Clinical Trial.JAMA internal medicine · 2023Trial
- Impact of mHealth on Medication Adherence in Older Adults with Chronic Diseases Facing Treatment Burden: A Systematic Review.Geriatrics (Basel, Switzerland) · 2026Review
- Restarting Medications After Deprescribing in Adults Discharged From Hospital to Skilled Nursing.JAMA network open · 2026Article
- Analysis of a medication discrepancy management platform in reducing medication discrepancy and influencing factors among elderly patients with polypharmacy.European journal of clinical pharmacology · 2025Article
- Article
- Delirium Prevention and Management in Older Adults in the Emergency Department.Emergency medicine clinics of North America · 2025Review
- Engagement of outpatient providers in a deprescribing trial for hospitalized older patients transitioning to post-acute care facilities.Health literacy and communication open · 2025Article
- Selective serotonin/serotonin-norepinephrine reuptake inhibitor serum concentrations' association with delirium duration.Journal of the American Geriatrics Society · 2024Article
- Emergency department visits and hospital readmissions after a deprescribing intervention among hospitalized older adults.Journal of the American Geriatrics Society · 2024Article
- Medication Discrepancies among Older Hospitalized Adults Discharged from Post-Acute Care Facilities to Home.Journal of the American Medical Directors Association · 2024Article
- Impact of an Area Agency on Aging pharmacist-led Community Care Transition Initiative.Journal of the American Pharmacists Association : JAPhAArticle
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundHospitalized older adults have a high prevalence of polypharmacy and medication inaccuracies. Gathering the best possible medication history (BPMH) is necessary to accurately identify each medication for multimorbid older adults. The objective was to describe a multipronged approach to obtaining the BPMH for hospitalized older adults, quantify the medication discrepancies identified through these sources, and explore factors associated with these discrepancies.
methodsCross-sectional analysis of 372 hospitalized older adults (age ≥ 50) transitioning to post-acute care as part of a randomized controlled trial to reduce medication burden. We used four information sources to yield a BPMH. Medication discrepancies at hospital admission were categorized as omissions, additions, and dose discrepancies after comparing alternate sources with the electronic medical record (EMR). Multivariate regression analysis, including patient factors (e.g., age, prehospital medication count, number of pharmacies), was performed to identify factors associated with the total count of medication discrepancies.
resultsNinety percent of participants had at least one medication discrepancy and 46% used more than one pharmacy. The majority of discrepancies were omissions. Among the entire cohort, there was a median of two omitted medications per patient across two alternate sources-pharmacy refill history and bedside interview. Lower age, greater total number of prehospital medications, and admission from assisted living or skilled nursing facility were significantly associated with greater medication discrepancies.
conclusionA multipronged and consistent approach to obtain a BPMH during hospitalization for multimorbid older adults revealed medication discrepancies that should be addressed prior to hospital discharge to support safe prescribing practices.
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