Evidence map›Paper›PMID 34966978›Full record

ArticleAAPS PharmSciTech2021

Scrutinizing the Feasibility of Nonionic Surfactants to Form Isotropic Bicelles of Curcumin: a Potential Antiviral Candidate Against COVID-19.

Dina B Mahmoud, Mohamed Mofreh Bakr, Ahmed A Al-Karmalawy, Yassmin Moatasim, Ahmed El Taweel, Ahmed Mostafa

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in AAPS PharmSciTech, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
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  18. Biological evaluation, docking studies, andJournal of enzyme inhibition and medicinal chemistry · 2023
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Dina B MahmoudDepartment of Pharmaceutics, Egyptian drug Authority (formerly known as National Organization for Drug Control and Research), Giza, Egypt. Dina.BahaaElDinMahmoudZaki@medizin.uni-leipzig.de.
Mohamed Mofreh BakrDepartment of Pharmaceutics, Egyptian drug Authority (formerly known as National Organization for Drug Control and Research), Giza, Egypt.
Ahmed A Al-KarmalawyDepartment of Pharmaceutical Medicinal Chemistry, Faculty of Pharmacy, Horus University-Egypt, New Damietta, 34518, Egypt.
Yassmin MoatasimCenter of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, 12622, Egypt.
Ahmed El TaweelCenter of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, 12622, Egypt.
Ahmed MostafaCenter of Scientific Excellence for Influenza Viruses, National Research Centre, Giza, 12622, Egypt. ahmed_elsayed@daad-alumni.de.
National Research Centre · EGNational Organization for Drug Control and Research · EGDamietta University · EG

Funding

Ministry of Scientific Research, Egypt 7303National Research Centre MP120801
6 · The paper itself

Abstract

Investigating bicelles as an oral drug delivery system and exploiting their structural benefits can pave the way to formulate hydrophobic drugs and potentiate their activity. Herein, the ability of non-ionic surfactants (labrasol

Indexed as

COVID-19CurcuminAntiviral AgentsFeasibility StudiesHumansMicellesMolecular Docking SimulationSARS-CoV-2Surface-Active AgentsAntiviral AgentsCurcuminMicellesSurface-Active AgentsBicellesMixed micellesMolecular dockingNon-ionic surfactantsSARS-CoV-2

Identifiers

PMID34966978
PMCPMC8716085
OpenAlexW4200525487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.