Evidence map›Paper›PMID 34966825›Full record

ArticleJournal of immunology research2021

TEX10 Promotes the Tumorigenesis and Radiotherapy Resistance of Urinary Bladder Carcinoma by Stabilizing XRCC6.

Sheng Luo, Wenjin Wang, Jingfang Feng, Rui Li

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Bladder (San Francisco, Calif.) · 2025
    Article
  7. Article
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sheng LuoDepartment of Urology, Xiangyang No. 1 People's Hospital, Hubei University of Medicine, Xiangyang, China.
Wenjin WangDepartment of Nephrology, Xiangyang No. 1 People's Hospital, Hubei University of Medicine, Xiangyang, China.
Jingfang FengDepartment of Nephrology, Xiangyang No. 1 People's Hospital, Hubei University of Medicine, Xiangyang, China.ORCID https://orcid.org/0000-0002-9961-2837
Rui LiDepartment of Urology, Xiangyang No. 1 People's Hospital, Hubei University of Medicine, Xiangyang, China.ORCID https://orcid.org/0000-0002-3067-3658
Hubei University of Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urinary bladder carcinoma refers to the commonest carcinoma with weak prognostic result for the patient as impacted by the limited treatment possibilities and challenging diagnosing process. Nevertheless, the molecular underpinning of bladder carcinoma malignant progression is still not clear. As a novel core part of pluripotency circuitry, testicular expression 10 (TEX10) plays an actively noticeable effect on reprogramming, early embryo development, and embryonic stem cell self-renewal. Nevertheless, TEX10 expressions and functions within bladder carcinoma are still not known. The present work is aimed at revealing TEX10 expression and biological function within urinary bladder carcinoma and elucidating the potential mechanisms. Results showed that TEX10 is abundant in urinary bladder carcinoma, and its protein level was related to poor disease-free survival in a positive manner. Reduced TEX10 level inhibited urinary bladder carcinoma cell proliferating process and metastasis in vitro and xenograft tumorigenicity in vivo. Notably, TEX10 might regulate carcinoma cell proliferating process and metastasis via XRCC6, thereby controlling the signaling of Wnt/

Indexed as

Biomarkers, TumorCell Line, TumorCell MovementCell Transformation, NeoplasticDisease SusceptibilityDNA End-Joining RepairGene Expression Regulation, NeoplasticHumansKu AutoantigenNuclear ProteinsRadiation ToleranceRNA StabilityUrinary Bladder NeoplasmsWnt Signaling PathwayBiomarkers, TumorKu AutoantigenNuclear ProteinsTEX10 protein, humanXrcc6 protein, human

Identifiers

PMID34966825
PMCPMC8712183
OpenAlexW4200573467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.