Evidence map›Paper›PMID 34966824›Full record

ArticleJournal of immunology research2021

Imbalance of the Gut Microbiota May Be Associated with Missed Abortions: A Perspective Study from a General Hospital of Hunan Province.

Bingsi Gao, Xingping Zhao, Xinyi Liu, Xuan Yang, Aiqian Zhang, Huan Huang, Yu-Ligh Liou, Dabao Xu

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Bingsi GaoDepartment of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, 138 Tongzipo Rd, Changsha, 410013 Hunan, China.ORCID https://orcid.org/0000-0002-6329-9076
Xingping ZhaoDepartment of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, 138 Tongzipo Rd, Changsha, 410013 Hunan, China.ORCID https://orcid.org/0000-0003-1071-4683
Xinyi LiuDepartment of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, 138 Tongzipo Rd, Changsha, 410013 Hunan, China.
Xuan YangCentral South University, Xiangya School of Medicine, 172 Tongzipo Rd, Changsha, 410013 Hunan, China.
Aiqian ZhangDepartment of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, 138 Tongzipo Rd, Changsha, 410013 Hunan, China.
Huan HuangDepartment of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, 138 Tongzipo Rd, Changsha, 410013 Hunan, China.
Yu-Ligh LiouXiangya Medical Laboratory, Central South University, Changsha, Hunan 410078, China.ORCID https://orcid.org/0000-0003-3994-6250
Dabao XuDepartment of Obstetrics and Gynecology, The Third Xiangya Hospital of Central South University, 138 Tongzipo Rd, Changsha, 410013 Hunan, China.ORCID https://orcid.org/0000-0002-8380-3057
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo conduct a preliminary investigation that shows the possible correlation between the change of gut microbiota and missed abortions (MAs), which further provides a new potential insight for the prevention and therapy of MAs.

methodOne hundred women, including 50 patients with MAs (case group) and 50 normal pregnant women (control group), were enrolled in the study. Fecal specimens were collected in the first trimester. Bacterial DNA was extracted, hybridized with primers of specific genes, and then detected by bacterial chip. The composition and the relative abundance of the gut microbiota were compared and analyzed. Furthermore, Kyoto Encyclopedia of Genes and Genomes enrichment analysis was used to explore the relative pathways.

results(1) The

conclusionThe high abundance of

Indexed as

Gastrointestinal MicrobiomeAbortion, MissedAdultBiodiversityChinaComputational BiologyDisease SusceptibilityDysbiosisFemaleHumansMetagenomicsMycoplasmaPregnancyRisk Factors

Identifiers

PMID34966824
PMCPMC8712186
OpenAlexW4200129998

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.