Evidence map›Paper›PMID 34966726›Full record

ReviewFrontiers in bioengineering and biotechnology2021

The Future of Personalized Medicine in Space: From Observations to Countermeasures.

Elizabeth Pavez Loriè, Sarah Baatout, Alexander Choukér, Judith-Irina Buchheim, Bjorn Baselet, Cinzia Dello Russo, Virginia Wotring, Monica Monici, Lucia Morbidelli, Dimitri Gagliardi and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.

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  11. Evaluation of theFrontiers in bioengineering and biotechnology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 6 countries.

Elizabeth Pavez LorièLeibniz Institute for Environmental Medicine, IUF, Düsseldorf, Germany.
Sarah BaatoutRadiobiology Unit, Belgian Nuclear Research Centre (SCK CEN), Mol, Belgium.
Alexander ChoukérLaboratory of Translational Research "Stress and Immunity", Department of Anesthesiology, Hospital of the Ludwig-Maximilians-University, Munich, Germany.
Judith-Irina BuchheimLaboratory of Translational Research "Stress and Immunity", Department of Anesthesiology, Hospital of the Ludwig-Maximilians-University, Munich, Germany.
Bjorn BaseletRadiobiology Unit, Belgian Nuclear Research Centre (SCK CEN), Mol, Belgium.
Cinzia Dello RussoDepartment of Healthcare Surveillance and Bioethics, Section of Pharmacology, Università Cattolica Del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Virginia WotringInternational Space University, Illkirch-Graffenstaden, France.
Monica MoniciASA Campus Joint Laboratory, ASA Research Division, Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.
Lucia MorbidelliDepartment Life Sciences, University of Siena, Siena, Italy.
Dimitri GagliardiManchester Institute of Innovation Research, Alliance Manchester Business School, The University of Manchester, Manchester, United Kingdom.
Julia Caroline StinglInstitute of Clinical Pharmacology, University Hospital of the RWTH Aachen, Aachen, Germany.
Leonardo SurdoSpace Applications Services NV/SA for the European Space Agency, Noordwijk, Netherlands.
Vincent Lai Ming YipMRC Centre for Drug Safety Science and Wolfson Centre for Personalized Medicine, Institute of Systems, Molecular and Integrative Biology (ISMIB), University of Liverpool, Liverpool, United Kingdom.
Ludwig-Maximilians-Universität München · DEUniversity of Liverpool · GBBelgian Nuclear Research Centre · BEEuropean Space Research and Technology Centre · NLGhent University · BEInternational Space University · FRLeibniz Institute of Environmental Medicine · DERWTH Aachen University · DEUniversity of Florence · ITUniversity of Manchester · GBUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of personalized medicine is to detach from a "one-size fits all approach" and improve patient health by individualization to achieve the best outcomes in disease prevention, diagnosis and treatment. Technological advances in sequencing, improved knowledge of omics, integration with bioinformatics and new

Indexed as

dermatologyfuture approachimmunologyin vitro modellingpersonalized medicinepharmacologyradiationspace biology

Identifiers

PMID34966726
PMCPMC8710508
OpenAlexW4200045121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.