Evidence map›Paper›PMID 34966613›Full record

ArticleCureus2021

Persistent Parosmia Caused By COVID-19 Infection: An Emerging Symptom.

Wael Khalifah, Basem Damanhouri, Bandar Abushal, Osama Marglani, Bashaer Alharbi, Murouj Almaghrabi, Rawan Alosaimy, Ahaad M Basahal

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Effects of nasal inflammation on the olfactory bulb.Journal of neuroinflammation · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Wael KhalifahOtolaryngology, Jeddah University, Jeddah, SAU.
Basem DamanhouriOtolaryngology, King Abdullah Medical City, Makkah, SAU.
Bandar AbushalOtolaryngology, Ministry of Health, Makkah, SAU.
Osama MarglaniOtolaryngology-Head & Neck Surgery, King Faisal Specialist Hospital & Research Center, Jeddah, SAU.
Bashaer AlharbiMedicine, College of Medicine, Umm Al-Qura University, Al-Abdia Main Campus, Makkah, SAU.
Murouj AlmaghrabiMedicine, College of Medicine, Umm Al-Qura University, Al-Abdia Main Campus, Makkah, SAU.
Rawan AlosaimyMedicine, College of Medicine, Umm Al-Qura University, Al-Abdia Main Campus, Makkah, SAU.
Ahaad M BasahalMedicine, College of Medicine, Umm Al-Qura University, Al-Abdia Main Campus, Makkah, SAU.
Jeddah University · SAMinistry of Health · BWKing Abdullah Medical City · SAKing Faisal Specialist Hospital & Research Centre · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives Coronavirus disease 2019 (COVID-19) is associated with several known signs and symptoms, including olfactory disturbances leading to anosmia and parosmia. This study aimed to evaluate the clinical features of the emerging symptoms of post-COVID-19 parosmia and to report the outcome of commonly used intervention methods. Methods The study's sample included post-COVID-19 patients who complained of parosmia, presented to otorhinolaryngology clinics at private tertiary care hospitals from December 2020 to April 2021. Patients' data were collected from the hospital system and through direct phone interviews. The Modified Arabic 20-Items Sino-Nasal Outcome Test (MA-SNOT-20) was used to measure the severity of rhinosinusitis symptoms. Results Twenty-one patients were included in the study, and their ages mainly ranged between 20 and 39 years (76.2%), predominantly females 19 (90.5%). Post the COVID-19 illness course, nearly half of the patients (9; 42.9%) reported full recovery of olfaction and taste senses. Nine cases (42.9%) received treatment with intranasal and oral steroids, of which only three cases (14.3%) noticed improvement. The remaining 12 cases (57.1%) did not receive any treatment, two of which improved (9.5%). The maximum MA-SNOT score was 37 while the minimum was 3, and eight patients (38.1%) scores were between one and 10 points. Conclusion Olfactory and taste dysfunctions are common symptoms of COVID-19. The emerging symptom of parosmia is worth reporting in the literature to increase the awareness of this particular symptom in this pandemic era. Many management strategies have been introduced that might be effective. However, further studies are needed to establish evidence-based management protocols.

Indexed as

anosmiacovid-19olfactory dysfunctionparosmiataste dysfunction

Identifiers

PMID34966613
PMCPMC8710301
OpenAlexW3216352765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.