Evidence map›Paper›PMID 34966529›Full record

ArticleFrontline gastroenterology2022

The dedicated iron deficiency anaemia clinic: a 15-year experience.

Helen Stone, Orouba Almilaji, Christopher John, Carla Smith, Susan L Surgenor, Lachlan Ayres, Elizabeth J Williams, Jonathon Snook

Open access · greenAbstract read
In one paragraph

Article in Frontline gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
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  5. Prevalence and patterns of testing for anaemia in primary care in England: a cohort study using an electronic health records database.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
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  12. Colorectal cancer and the blood loss paradox.Frontline gastroenterology · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Modelling the episodes of care for iron deficiency anemia patients in a secondary-care center using continuous-time multistate Markov chain.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Helen StoneGastroenterology Unit, Poole Hospital NHS Foundation Trust, Poole, UK.
Orouba AlmilajiGastroenterology Unit, Poole Hospital NHS Foundation Trust, Poole, UK.
Christopher JohnGastroenterology Unit, Poole Hospital NHS Foundation Trust, Poole, UK.
Carla SmithGastroenterology Unit, Poole Hospital NHS Foundation Trust, Poole, UK.
Susan L SurgenorGastroenterology Unit, Poole Hospital NHS Foundation Trust, Poole, UK.
Lachlan AyresGastroenterology Unit, Poole Hospital NHS Foundation Trust, Poole, UK.
Elizabeth J WilliamsGastroenterology Unit, Poole Hospital NHS Foundation Trust, Poole, UK.
Jonathon SnookGastroenterology Unit, Poole Hospital NHS Foundation Trust, Poole, UK.ORCID 0000-0002-3172-2722
University Gastroenterology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo report our cumulative experience from a dedicated iron deficiency anaemia (IDA) clinic over the last 15 years-with particular emphasis on referral rate, uptake of investigation, impact on endoscopy services, diagnostic yield of gastrointestinal (GI) investigation and the issue of recurrent IDA.

methodA series of analyses of a register of 2808 referrals to the Poole IDA clinic between 2004 and 2018.

resultsThe study population of 2808 had a sex ratio of 1.9 (female/male ratio) and a median age of 72 years (IQR: 60-79). A rising referral rate over the study period appears to be plateauing at around 2 cases per 1000 population per annum. On the basis of a snapshot audit, investigation of IDA may now account for over 20% of all diagnostic endoscopies.Overall, 86% of cases underwent examination of the upper and lower GI tract. Significant GI pathology was identified in 27% of the investigated cohort. Adenocarcinoma of the upper or lower GI tract was found in 8.3%, the majority in the right colon. The prevalence of recurrent IDA was estimated at 12.4%, and the results of investigation of this subgroup are reported.

conclusionUnexplained IDA is common, particularly in those over 60 years, and may be the first indication of underlying GI malignancy in over 8% of cases. Unresolved challenges include accommodating the resulting endoscopy workload, establishing a risk/benefit ratio for investigating those with major comorbidities and the management of recurrent IDA.

Indexed as

gastrointestinal canceriron deficiency

Identifiers

PMID34966529
PMCPMC8666872
OpenAlexW3085719515

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.