Evidence map›Paper›PMID 34966466›Full record

ArticleDisease markers2021

Governor Vessel Moxibustion Therapy Improves Microbiota Structure in Ankylosing Spondylitis Patients.

Guodong Sun, Qingbo Wang, Shengnan Cao, Haidong Xu, Yan Zhao

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Guodong SunAcademy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin 300072, China.ORCID https://orcid.org/0000-0002-0919-7925
Qingbo WangShandong First Medical University, Jinan, Shandong 250117, China.
Shengnan CaoShandong University of Traditional Chinese Medicine, Jinan, Shandong 250355, China.ORCID https://orcid.org/0000-0002-7341-5608
Haidong XuDepartment of Rehabilitation Medicine, Affiliated Hospital of Shandong Academy of Medical Sciences, Jinan, Shandong 250031, China.
Yan ZhaoBiomedical Sciences College & Shandong Medicinal Biotechnology Centre, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong 250062, China.ORCID https://orcid.org/0000-0002-5843-3816
Shandong First Medical University · CNAffiliated Hospital of Shandong Academy of Medical Sciences · CNShandong University of Traditional Chinese Medicine · CNTianjin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClinical studies have shown that ankylosing spondylitis (AS) could be significantly improved by Governor Vessel moxibustion (GVM) therapy.

objectiveStudy whether GVM therapy alleviates the clinical symptoms of AS by modulating intestinal microbiota.

methodsA total of 9 AS patients and 9 paired healthy individuals were enrolled, and GVM therapy was provided to the AS patients. Stool, urine, and saliva samples from the healthy individuals and the AS patients before and after GVM therapy were collected, and 16S rRNA gene sequencing was performed for microbiota analysis.

resultsWe found that GVM therapy can significantly alleviate the symptoms of AS, such as diarrhea, abdominal pain, and bloating. GVM therapy also decreased the abundances of

conclusionsOverall, these findings demonstrate that GVM therapy can alleviate AS clinical symptoms, and at the same time, it improves the microbial structure of microbiota in AS patients. This trial is registered with Chinese Clinical Trial Registry ChiCTR2100051907.

Indexed as

Medicine, Chinese TraditionalMoxibustionAbdominal PainAdultDiarrheaFecesFemaleGastrointestinal MicrobiomeHumansMaleMiddle AgedRNA, Ribosomal, 16SSalivaSpondylitis, AnkylosingUrineRNA, Ribosomal, 16S

Identifiers

PMID34966466
PMCPMC8712134
OpenAlexW4200306684

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.