Evidence map›Paper›PMID 34966388›Full record

ArticleFrontiers in immunology2021

BpOmpW Antigen Stimulates the Necessary Protective T-Cell Responses Against Melioidosis.

Julen Tomás-Cortázar, Lorenzo Bossi, Conor Quinn, Catherine J Reynolds, David K Butler, Niamh Corcoran, Maitiú Ó Murchú, Eve McMahon, Mahavir Singh, Patpong Rongkard and 8 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Laboratory diagnosis of melioidosis.PLoS neglected tropical diseases · 2025
    Review
  2. Article
  3. Review
  4. Article
  5. Vaccines · 2024
    Review
  6. Burkholderia pseudomallei and melioidosis.Nature reviews. Microbiology · 2024
    Review
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 5 countries.

Julen Tomás-CortázarConway Institute of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland.
Lorenzo BossiImmunxperts SA, a Nexelis Company, Gosselies, Belgium.
Conor QuinnConway Institute of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland.
Catherine J ReynoldsDepartment of Infectious Disease, Imperial College London, London, United Kingdom.
David K ButlerDepartment of Infectious Disease, Imperial College London, London, United Kingdom.
Niamh CorcoranConway Institute of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland.
Maitiú Ó MurchúConway Institute of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland.
Eve McMahonConway Institute of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland.
Mahavir SinghLIONEX Diagnostics and Therapeutics GmbH, Brunswick, Germany.
Patpong RongkardMahidol-Oxford Tropical Medicine Research Unit, Bangkok, Thailand.
Juan AnguitaInflammation and Macrophage Plasticity Lab, CIC bioGUNE-BRTA (Basque Research and Technology Alliance), Derio, Spain.
Alfonso BlancoConway Institute of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland.
Susanna J DunachieMahidol-Oxford Tropical Medicine Research Unit, Bangkok, Thailand.
Daniel AltmannDepartment of Infectious Disease, Imperial College London, London, United Kingdom.
Rosemary J BoytonDepartment of Infectious Disease, Imperial College London, London, United Kingdom.
Johan ArnoldImmunxperts SA, a Nexelis Company, Gosselies, Belgium.
Severine GiltaireImmunxperts SA, a Nexelis Company, Gosselies, Belgium.
Siobhán McCleanConway Institute of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland.
University College Dublin · IEHarefield Hospital · GBMahidol Oxford Tropical Medicine Research Unit · THCIC bioGUNE · ESLionex (Germany) · DE

Funding

Department of Health NIHR300791Medical Research Council MC_PC_17218Medical Research Council MR/R005850/1Wellcome TrustWellcome Trust 209274/Z/17/ZWellcome Trust WT100174/Z/12/Z
6 · The paper itself

Abstract

Melioidosis is a potentially fatal bacterial disease caused by

Indexed as

AnimalsAntigens, BacterialBacterial Outer Membrane ProteinsBacterial VaccinesBurkholderia pseudomalleiCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCells, CulturedDiabetes Mellitus, Type 2HumansInterferon-gammaKiller Cells, NaturalMaleMelioidosisMiceMice, Inbred C57BLAntigens, BacterialBacterial Outer Membrane ProteinsBacterial VaccinesInterferon-gammaBurkholderia pseudomalleiIFN-γmelioidosisT-cell responsestype 2 diabetesvaccine

Identifiers

PMID34966388
PMCPMC8710444
OpenAlexW4200079674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.