Evidence map›Paper›PMID 34966362›Full record

ArticleFrontiers in microbiology2021

Epidemic Preparedness-

Ilaria Varotto-Boccazzi, Alessandro Manenti, Francesca Dapporto, Louise J Gourlay, Beatrice Bisaglia, Paolo Gabrieli, Federico Forneris, Silvia Faravelli, Valentina Bollati, Diego Rubolini and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Vaccines · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

Ilaria Varotto-BoccazziDepartment of Biosciences, University of Milan, Milan, Italy.
Alessandro ManentiVisMederi Research, Siena, Italy.
Francesca DapportoVisMederi Research, Siena, Italy.
Louise J GourlayDepartment of Biosciences, University of Milan, Milan, Italy.
Beatrice BisagliaDepartment of Biosciences, University of Milan, Milan, Italy.
Paolo GabrieliDepartment of Biosciences, University of Milan, Milan, Italy.
Federico FornerisThe Armenise-Harvard Laboratory of Structural Biology, Department of Biology and Biotechnology "L. Spallanzani", University of Pavia, Pavia, Italy.
Silvia FaravelliThe Armenise-Harvard Laboratory of Structural Biology, Department of Biology and Biotechnology "L. Spallanzani", University of Pavia, Pavia, Italy.
Valentina BollatiDepartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Diego RuboliniDepartment of Environmental Science and Policy, University of Milan, Milan, Italy.
Gianvincenzo ZuccottiDepartment of Biomedical and Clinical Science "L. Sacco", University of Milan, Milan, Italy.
Emanuele MontomoliVisMederi Research, Siena, Italy.
Sara EpisDepartment of Biosciences, University of Milan, Milan, Italy.
Claudio BandiDepartment of Biosciences, University of Milan, Milan, Italy.
University of Milan · ITUniversity of Pavia · ITVisMederi Research · ITIstituto Nazionale Genetica Molecolare · ITUniversity of Siena · ITWater Research Institute · IT

Funding

NIAID NIH HHS HHSN272201400008C
6 · The paper itself

Abstract

To detect and prevent emerging epidemics, discovery platforms are urgently needed, for the rapid development of diagnostic assays. Molecular diagnostic tests for COVID-19 were developed shortly after the isolation of SARS-CoV-2. However, serological tests based on antiviral antibody detection, revealing previous exposure to the virus, required longer testing phases, due to the need to obtain correctly folded and glycosylated antigens. The delay between the identification of a new virus and the development of reliable serodiagnostic tools limits our readiness to tackle future epidemics. We suggest that the protozoan

Indexed as

cell-factoryepidemicsLeishmania tarentolae expression systemprotein antigensSARS-CoV-2serodiagnostics

Identifiers

PMID34966362
PMCPMC8710741
OpenAlexW4200247815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.