Evidence map›Paper›PMID 34966274›Full record

ArticleFrontiers in pharmacology2021

Tanyu Tongzhi Formula Delays Atherosclerotic Plaque Progression by Promoting Alternative Macrophage Activation

Lan Ma, Xiaoce Dai, Chenxia Wu, Mingshuang Li, Hongzhuan Sheng, Wei Mao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Lan MaDepartment of Cardiology, Affiliated Hospital of Nantong University, Nantong, China.
Xiaoce DaiDepartment of Cardiology, First Affiliated Hospital of Jiaxing University, Jiaxing, China.
Chenxia WuDepartment of Cardiology, First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Mingshuang LiDepartment of Cardiology, First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Hongzhuan ShengDepartment of Cardiology, Affiliated Hospital of Nantong University, Nantong, China.
Wei MaoDepartment of Cardiology, First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Zhejiang Chinese Medical University · CNAffiliated Hospital of Nantong University · CNFirst Hospital of Jiaxing · CNIntegrated Chinese Medicine (China) · CNNantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We previously demonstrated that the Tanyu Tongzhi Formula (TTF) significantly alleviated the clinical symptoms of patients with coronary heart disease and lowered serum lipid and inflammatory factor levels in patients with coronary heart disease and atherosclerosis model rats. However, the mechanism underlying TTF remains unknown. In this study, we examined the effect of TTF on atherosclerotic plaques in ApoE

Indexed as

alternative macrophage activationatherosclerosisPPARγTanyu Tongzhi formulatraditional Chinese medicine

Identifiers

PMID34966274
PMCPMC8711052
OpenAlexW4200578732

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.