ArticleFrontiers in aging neuroscience2021
Local Brain-Age: A U-Net Model.
Article in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- BrainAGE, brain health, and mental disorders: A systematic review.Neuroscience and biobehavioral reviews · 2024Pooled it
- Brain ageing in schizophrenia: evidence from 26 international cohorts via the ENIGMA Schizophrenia consortium.Molecular psychiatry · 2023Pooled it
- Brain responses to intermittent fasting and the healthy living diet in older adults.Cell metabolism · 2024Trial
- Genome-wide analysis of subcortical aging identifies a spatially structured pattern of genetic associations.GeroScience · 2026Article
- Deep neural networks and genome-wide associations reveal the polygenic architecture of local brain aging.GeroScience · 2026Article
- A Lightweight ScaleDense-Transformer Framework with Auxiliary Quantum-Inspired Bottleneck Module for Whole-Lifespan Brain Age Prediction.Brain sciences · 2026Article
- Spatial heterogeneity and subtypes of functional connectivity development in youth.Nature communications · 2026Article
- Article
- Regional brain aging patterns reveal disease-specific pathways of neurodegeneration.medRxiv : the preprint server for health sciences · 2025Article
- Individual-level brain phenotypes in first-episode mania: normative modelling of brain morphometry and brainAGE.BJPsych open · 2025Article
- Metabolic Status Modulates Global and Local Brain Age Estimates in Overweight and Obese Adults.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Article
- A review of artificial intelligence-based brain age estimation and its applications for related diseases.Briefings in functional genomics · 2025Review
- Unravelling pathological ageing with brain age gap estimation in Alzheimer's disease, diabetes and schizophrenia.Brain communications · 2025Article
- Low-Rank Tensor Fusion for Enhanced Deep Learning-Based Multimodal Brain Age Estimation.Brain sciences · 2024Article
- Exploring associations between psychotic experiences and structural brain age: a population-based study in late adolescence.medRxiv : the preprint server for health sciences · 2024Article
- Machine Learning and Deep Learning Approaches in Lifespan Brain Age Prediction: A Comprehensive Review.Tomography (Ann Arbor, Mich.) · 2024Review
- Predicting brain age using Tri-UNet and various MRI scale features.Scientific reports · 2024Article
- Modeling brain sex in the limbic system as phenotype for female-prevalent mental disorders.Biology of sex differences · 2024Article
- Accelerated Brain Aging Mediates the Association Between Psychological Profiles and Clinical Pain in Knee Osteoarthritis.The journal of pain · 2024Article
- Geroscience-Centric Perspective for Geriatric Psychiatry: Integrating Aging Biology With Geriatric Mental Health Research.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
We propose a new framework for estimating neuroimaging-derived "brain-age" at a local level within the brain, using deep learning. The local approach, contrary to existing global methods, provides spatial information on anatomical patterns of brain ageing. We trained a U-Net model using brain MRI scans from
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.