Trial reportScientific reports2021
Investigation of possible underlying mechanisms behind water-induced glucose reduction in adults with high copeptin.
Trial report in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Copeptin as a dual biomarker in type 2 diabetes: association with glycemic control and diabetic kidney disease.BMC endocrine disorders · 2026Article
- Apparently healthy young black adults report lower total fluid intake and exhibit higher plasma copeptin than young White adults.Nutrition research (New York, N.Y.) · 2025Article
- Relationship between fluid intake, hydration status and cortisol dynamics in healthy, young adult males.Comprehensive psychoneuroendocrinology · 2025Article
- Long-term health outcomes associated with hydration status.Nature reviews. Nephrology · 2024Review
- THIRSTY FOR FRUCTOSE: Arginine Vasopressin, Fructose, and the Pathogenesis of Metabolic and Renal Disease.Frontiers in cardiovascular medicine · 2022Review
- Association between Copeptin and Metabolic Syndrome: A Systematic Review.Journal of nutrition and metabolism · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Elevated copeptin, a surrogate marker of vasopressin, is linked to low water intake and increased diabetes risk. Water supplementation in habitual low-drinkers with high copeptin significantly lowers both fasting plasma (fp) copeptin and glucose. This study aims at investigating possible underlying mechanisms. Thirty-one healthy adults with high copeptin (> 10.7 pmol·L
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.