Evidence map›Paper›PMID 34966177›Full record

ArticleScientific reports2021

Kidney biopsy-based epidemiologic analysis shows growing biopsy rate among the elderly.

Adél Molnár, Mbuotidem Jeremiah Thomas, Attila Fintha, Magdolna Kardos, Deján Dobi, András Tislér, Nóra Ledó

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

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  9. Incidence and outcomes of kidney replacement therapy for end-stage kidney disease due to primary glomerular disease in Europe: findings from the ERA Registry.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Adél MolnárDepartment of Internal Medicine and Oncology, Faculty of Medicine, Semmelweis University, Korányi Sándor utca 2/a, Budapest, 1083, Hungary.
Mbuotidem Jeremiah ThomasInstitute of Translational Medicine, Semmelweis University, Budapest, Hungary.
Attila Fintha2nd Department of Pathology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.
Magdolna Kardos2nd Department of Pathology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.
Deján Dobi2nd Department of Pathology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.
András TislérDepartment of Internal Medicine and Oncology, Faculty of Medicine, Semmelweis University, Korányi Sándor utca 2/a, Budapest, 1083, Hungary.
Nóra LedóDepartment of Internal Medicine and Oncology, Faculty of Medicine, Semmelweis University, Korányi Sándor utca 2/a, Budapest, 1083, Hungary. ledo.nora@med.semmelweis-univ.hu.
Semmelweis University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systematic registration and examination of biopsy-related data in Central and Eastern Europe are scarce, while the health condition of the population is worse compared to other more developed countries. We aim to create a database and analyze the distribution and temporal variation of the renal biopsy diagnoses in Hungary, including the effect of the recent coronavirus pandemic. The diagnoses were standardized according to the recommendation of the European Renal Association. Native biopsy samples processed between January 1, 2006, and December 31, 2020, were analyzed. During the 15 years, 2140 native kidney biopsies were performed. The number of samples increased from 24.5 to 57.9 per million person-years and the median age from 37 to 51 years (p < 0.0001). The predominance of glomerular diseases was stable. The most frequent glomerulopathy was IgA nephropathy (21.5%), followed by focal segmental glomerulosclerosis (17.7%), and membranous nephropathy (15.7%). Trends showed the rise of ANCA-associated vasculitis. During the coronavirus pandemic, there was a decrease in the number of kidney biopsies and the proportion of membranous nephropathies. The diagnostic trends in our database showed increasing biopsy rates among the elderly and the growing frequencies of age-related diseases, which emphasizes the importance of altering medical focus according to demographic changes in this area.

Indexed as

AdultAge DistributionBiopsyFemaleGlomerulonephritisGlomerulonephritis, MembranousHumansHungaryIncidenceKidneyKidney DiseasesMaleMiddle AgedNephrectomyRetrospective Studies

Identifiers

PMID34966177
PMCPMC8716536
OpenAlexW4200111113

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.