Evidence map›Paper›PMID 34965977›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2022

Cortical Granularity Shapes the Organization of Afferent Paths to the Amygdala and Its Striatal Targets in Nonhuman Primate.

A C McHale, Y T Cho, J L Fudge

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Functional Heterogeneity within the Primate Ventral Striatum for Motivational Regulation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Cellular Diversity in Human Subgenual Anterior Cingulate and Dorsolateral Prefrontal Cortex by Single-Nucleus RNA-Sequencing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  8. Brain tract structure predicts relapse to stimulant drug use.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

A C McHaleDepartment of Neuroscience, University of Rochester, Rochester NY 14642.
Y T ChoDepartment of Psychiatry, University of Rochester, Rochester, NY 14642.
J L FudgeDepartment of Neuroscience, University of Rochester, Rochester NY 14642 julie_fudge@urmc.rochester.edu.ORCID 0000-0003-4783-8014
University of Rochester · USUniversity of Rochester Medical Center · US

Funding

TEMPORAL LOBE PATHWAYS THROUGH THE DOPAMINE SYSTEMR01MH063291 · NIMH · UNIVERSITY OF ROCHESTER · PI FUDGE, JULIE L. · 2001 to 2014
$3.6M
Resolving amygdala microcircuits: implications for functionR01MH130608 · NIMH · UNIVERSITY OF ROCHESTER · PI JULIE L. FUDGE · 2022 to 2026
$2.6M
Integrating social networks through amygdalostriatal pathsR01MH105624 · NIMH · UNIVERSITY OF ROCHESTER · PI FUDGE, JULIE L. · 2014 to 2018
$2.0M
NIMH NIH HHS R01 MH063291NIMH NIH HHS R01 MH105624NIMH NIH HHS R01 MH130608
6 · The paper itself

Abstract

The prefrontal cortex (PFC) and insula, amygdala, and striatum form interconnected networks that drive motivated behaviors. We previously found a connectional trend in which granularity of the ventromedial and orbital PFC/insula predicted connections to the amygdala, and also the breadth of amygdalo-striatal efferents, including projections beyond the "classic" ventral striatum. To further interrogate connectional relationships among the cortex, amygdala, and striatum, and to further define the "limbic" (amygdala-recipient) striatum, we conducted tract tracing studies in two cohorts of macaques (male

Indexed as

AmygdalaCorpus StriatumAnimalsBasal GangliaFemaleLimbic SystemMacacaMaleNeural Pathwaysamygdalaconnectivity“limbic” striatumneuroanatomyprefrontal cortexprimate

Identifiers

PMID34965977
PMCPMC8883863
OpenAlexW4200587712

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.