Evidence map›Paper›PMID 34965942›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2022

From Basic Science to Clinical Translation in Kidney Cancer: A Report from the Second Kidney Cancer Research Summit.

Toni K Choueiri, Laurence Albiges, Michael B Atkins, Ziad Bakouny, Gennady Bratslavsky, David A Braun, Naomi B Haas, John B A G Haanen, A Ari Hakimi, Michael A S Jewett and 16 more

Abstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Trial
  2. Transcriptomic Correlates of Tumor Cell PD-L1 Expression and Response to Nivolumab Monotherapy in Metastatic Clear Cell Renal Cell Carcinoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2022
    Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Toni K ChoueiriDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Laurence AlbigesDepartment of Medical Oncology, Gustave Roussy, Université Paris-Saclay, Villejuif, France.
Michael B AtkinsGeorgetown Lombardi Comprehensive Cancer Center, Washington, DC.ORCID 0000-0003-3901-9924
Ziad BakounyDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.ORCID 0000-0003-1906-5704
Gennady BratslavskyDepartment of Urology, State University of New York (SUNY) Upstate Medical University, Syracuse, New York.ORCID 0000-0002-2712-4375
David A BraunDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Naomi B HaasDivision of Hematology and Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0001-8907-7968
John B A G HaanenDepartment of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.
A Ari HakimiDepartment of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York.
Michael A S JewettDivision of Urology, Department of Surgery, Princess Margaret Cancer Centre, Toronto, Ontario, Canada.ORCID 0000-0001-7162-5380
Eric JonaschDepartment of Genitourinary Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.
William G KaelinDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Payal KapurDepartment of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas.ORCID 0000-0002-4239-0495
Chris LabakiDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.ORCID 0000-0002-9584-8455
Bryan LewisKidneyCAN, Philadelphia, Pennsylvania.
David F McDermottDivision of Medical Oncology, Beth Israel Deaconess Medical Center, Dana-Farber/Harvard Cancer Center, Boston, Massachusetts.
Sumanta K PalDepartment of Medical Oncology and Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, California.
Kevin PelsDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.ORCID 0000-0002-3214-379X
Susan PoteatKidneyCAN, Philadelphia, Pennsylvania.
Thomas PowlesBarts Cancer Institute, Queen Mary University of London, London, United Kingdom.
W Kimryn RathmellDepartment of Medicine, Vanderbilt University Medical Center (VUMC), Nashville, Tennessee.ORCID 0000-0002-4984-0225
Brian I RiniDepartment of Medicine, Vanderbilt University Medical Center (VUMC), Nashville, Tennessee.
Sabina SignorettiDepartment of Pathology, Brigham and Women's Hospital, Boston, Massachusetts.ORCID 0000-0002-5000-9105
Nizar M TannirDepartment of Genitourinary Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Robert G UzzoDepartment of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Hans J HammersDivision of Hematology-Oncology, University of Texas Southwestern Medical Center, Dallas, Texas.

Funding

Treating the P13-Kinase/AKTP50CA101942 · NCI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI David McDermott · 2003 to 2026
$53.4M
The von Hippel-Lindau Tumor Suppressor Gene and Kidney Cancer: Insights into Oxygen Sensing and Treating Cancers Caused by Undruggable MutationsR35CA210068 · NCI · DANA-FARBER CANCER INST · PI WILLIAM G. KAELIN · 2016 to 2026
$10.8M
NCI NIH HHS P50 CA101942NCI NIH HHS R35 CA210068
6 · The paper itself

Abstract

The second Kidney Cancer Research Summit was held virtually in October 2020. The meeting gathered worldwide experts in the field of kidney cancer, including basic, translational, and clinical scientists as well as patient advocates. Novel studies were presented, addressing areas of unmet need related to different topics. These include novel metabolic targets, promising immunotherapeutic regimens, predictive genomic and transcriptomic biomarkers, and variant histologies of renal cell carcinoma (RCC). With the development of pioneering technologies, and an unprecedented commitment to kidney cancer research, the field has tremendously evolved. This perspective aims to summarize the different sessions of the conference, outline major advances in the understanding of RCC and discuss current challenges faced by the field.

Indexed as

Biomedical ResearchCarcinoma, Renal CellKidney NeoplasmsFemaleGenomicsHumansMale

Identifiers

PMID34965942
PMCPMC9223120

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.