Evidence map›Paper›PMID 34965891›Full record

ReviewTropical medicine and health2021

The deuce-ace of Lassa Fever, Ebola virus disease and COVID-19 simultaneous infections and epidemics in West Africa: clinical and public health implications.

Nnabueze Darlington Nnaji, Helen Onyeaka, Rine Christopher Reuben, Olivier Uwishema, Chinasa Valerie Olovo, Amarachukwu Anyogu

Open access · goldAbstract readReview
In one paragraph

Review in Tropical medicine and health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Views of Nigerian civil servants about compulsory COVID-19 vaccination: A qualitative study.African journal of primary health care & family medicine · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Rise of Marburg virus in Africa: a call for global preparedness.Annals of medicine and surgery (2012) · 2023
    Article
  13. Article
  14. Review
  15. Article
  16. The roadmap of bioeconomy in China.Engineering biology · 2022
    Review
  17. Article
  18. Article
  19. Crimean-Congo haemorrhagic fever during the COVID-19 pandemic in Africa: Efforts, recommendations and challenges at hand.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 7 countries.

Nnabueze Darlington NnajiDepartment of Microbiology, University of Nigeria, Nsukka, Nigeria.ORCID http://orcid.org/0000-0002-1656-6194
Helen OnyeakaSchool of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.ORCID http://orcid.org/0000-0003-3846-847X
Rine Christopher ReubenGerman Centre for Integrative Biodiversity Research (iDiv), Halle-Jena-Leipzig, Leipzig, Germany.
Olivier UwishemaOli Health Magazine Organization, Research and Education, Kigali, Rwanda. uwolivier1@ktu.edu.tr.ORCID http://orcid.org/0000-0002-0692-9027
Chinasa Valerie OlovoDepartment of Microbiology, University of Nigeria, Nsukka, Nigeria.
Amarachukwu AnyoguSchool of Biomedical Sciences, University of West London, London, W5 5RF, UK.ORCID http://orcid.org/0000-0001-9652-7728
German Centre for Integrative Biodiversity Research · DEJiangsu University · CNKaradeniz Technical University · TRUniversity of Birmingham · GBUniversity of Nigeria · NGUniversity of West London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Globally, the prevailing COVID-19 pandemic has caused unprecedented clinical and public health concerns with increasing morbidity and mortality. Unfortunately, the burden of COVID-19 in Africa has been further exacerbated by the simultaneous epidemics of Ebola virus disease (EVD) and Lassa Fever (LF) which has created a huge burden on African healthcare systems. As Africa struggles to contain the spread of the second (and third) waves of the COVID-19 pandemic, the number of reported cases of LF is also increasing, and recently, new outbreaks of EVD. Before the pandemic, many of Africa's frail healthcare systems were already overburdened due to resource limitations in staffing and infrastructure, and also, multiple endemic tropical diseases. However, the shared epidemiological and pathophysiological features of COVID-19, EVD and LF as well their simultaneous occurrence in Africa may result in misdiagnosis at the onset of infection, an increased possibility of co-infection, and rapid and silent community spread of the virus(es). Other challenges include high population mobility across porous borders, risk of human-to-animal transmission and reverse zoonotic spread, and other public health concerns. This review highlights some major clinical and public health challenges toward responses to the COVID-19 pandemic amidst the deuce-ace of recurrent LF and EVD epidemics in Africa. Applying the One Health approach in infectious disease surveillance and preparedness is essential in mitigating emerging and re-emerging (co-)epidemics in Africa and beyond.

Indexed as

COVID-19Ebola virus diseaseEpidemicsLassa FeverPandemicWest Africa

Identifiers

PMID34965891
PMCPMC8716304
OpenAlexW4200094721

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.