ReviewAnimal microbiome2021
Possibilities and limits for using the gut microbiome to improve captive animal health.
Review in Animal microbiome, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
47 citing papers in PubMed, 67 citations in OpenAlex.
- Gut Microbiota Composition and Predicted Functional Profiles: Functional Adaptation of Overwintering Whooper Swans (Animals : an open access journal from MDPI · 2026Article
- Fecal Microbiomes in Ex Situ-Managed Mammals: Captivity-Associated Shifts and Links to Welfare, Stress, and Reproductive Performance.Animals : an open access journal from MDPI · 2026Review
- Microbial Variability in Zoo-Housed Alaotran Gentle Lemurs: Host-Associated Factors and Environmental Influences.American journal of primatology · 2026Article
- Exposure to Environmental Microbes Alters Responsiveness of Tadpole Gut Microbiome to Dietary Tannins.Integrative zoology · 2026Article
- Ecological dynamics of the Atlantic salmon gut microbiota across developmental phases and geographic regions.Communications biology · 2026Article
- Review
- Effects of environmental setting and diet on the gut microbial ecology of eastern hellbenders (Cryptobranchus alleganiensis alleganiensis).Animal microbiome · 2026Article
- Grass supplementation to a pellet-based diet fails to enrich gut microbiomes with wild-like functions in captive-bred hares.Microbiology spectrum · 2026Article
- Characterization of a Core Fungal Community and Captivity-Induced Gut "Mycobiome" Change in Fowler's Toad (Ecology and evolution · 2026Article
- Gut Microbiota of Captive and Wild Siberian Cranes and Links to Soil in Poyang Lake Wetlands.Animals : an open access journal from MDPI · 2026Article
- Article
- Variation in zoo diets, offerings of leafy browse, and body condition scores in Matschie's tree kangaroos (PeerJ · 2026Article
- Microbiota in the Early Lives of Sheep: A Short Overview on the Rumen Microbiota.Animals : an open access journal from MDPI · 2025Review
- Effects of naturalistic housing conditions on amphibian growth and microbiome in captivity.Animal microbiome · 2025Article
- Unravelling the impacts of captivity on saltwater crocodile (Crocodylus porosus) cloacal bacterial communities and physiology.FEMS microbiology ecology · 2025Article
- Isolation, Identification, and Antimicrobial Susceptibility ofVeterinary sciences · 2025Article
- Wild gut microbiome suppresses the potentially opportunistic pathogen Aeromonas in medaka under domesticated rearing conditions.Animal microbiome · 2025Article
- Natal soil consumption shifts gut microbiome in captive Ōkārito kiwi (Apteryx rowi).Animal microbiome · 2025Article
- Review
- Pondering Ponds: Exploring Correlations Between Cloacal Microbiota and Blood Metabolome in Freshwater Turtles.Microbial ecology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Because of its potential to modulate host health, the gut microbiome of captive animals has become an increasingly important area of research. In this paper, we review the current literature comparing the gut microbiomes of wild and captive animals, as well as experiments tracking the microbiome when animals are moved between wild and captive environments. As a whole, these studies report highly idiosyncratic results with significant differences in the effect of captivity on the gut microbiome between host species. While a few studies have analyzed the functional capacity of captive microbiomes, there has been little research directly addressing the health consequences of captive microbiomes. Therefore, the current body of literature cannot broadly answer what costs, if any, arise from having a captive microbiome in captivity. Addressing this outstanding question will be critical to determining whether it is worth pursuing microbial manipulations as a conservation tool. To stimulate the next wave of research which can tie the captive microbiome to functional and health impacts, we outline a wide range of tools that can be used to manipulate the microbiome in captivity and suggest a variety of methods for measuring the impact of such manipulation preceding therapeutic use. Altogether, we caution researchers against generalizing results between host species given the variability in gut community responses to captivity and highlight the need to understand what role the gut microbiome plays in captive animal health before putting microbiome manipulations broadly into practice.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.