ArticleBMC oral health2021
Oral and dental manifestations of celiac disease in children: a case-control study.
Article in BMC oral health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Relative risk of oral manifestations with celiac disease: a systematic review and meta-analysis.BMC gastroenterology · 2026Pooled it
- Periodontal Status of Patients with Celiac Disease and Non-Celiac Gluten Sensitivity: A Literature Review.Journal of clinical medicine · 2026Review
- Challenges in the Pediatric Celiac Disease Diagnosis: An Up-to-Date Review.Diagnostics (Basel, Switzerland) · 2025Review
- Importance of celiac disease oral manifestations in pediatric patients: A systematic review.World journal of clinical pediatrics · 2025Article
- Associations between Celiac Disease, Extra-Gastrointestinal Manifestations, and Gluten-Free Diet: A Narrative Overview.Nutrients · 2024Review
- Evaluation of children's oral diagnosis and treatment using imaging examination using AI based Internet of Things.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024Article
- Prediction model of dental caries in 12-year-old children in Sichuan Province based on machine learning.Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2023Article
- Otorhinolaryngological Manifestations and Esophageal Disorders in Celiac Disease: A Narrative Review.Journal of clinical medicine · 2023Review
- Nutrition and oral health in children with recently and previously diagnosed celiac disease.Clinical oral investigations · 2023Article
- Beyond the Gut: A Systematic Review of Oral Manifestations in Celiac Disease.Journal of clinical medicine · 2023Review
- Dental Manifestations and Celiac Disease-An Overview.Journal of clinical medicine · 2023Review
- Oral health-related quality of life in children with celiac disease.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- New Approach to Addison Disease: Oral Manifestations Due to Endocrine Dysfunction and Comorbidity Burden.Diagnostics (Basel, Switzerland) · 2022Review
- Who to screen and how to screen for celiac disease.World journal of gastroenterology · 2022Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCeliac disease (CD) is an immune-mediated enteropathy. CD may also involve complications with the oral cavity, which can result in various dental and oral pathologies. There are currently a limited number of studies on the oral manifestation of CD. This study aims to compare the oral manifestations of children with CD against healthy controls in Saudi Arabia. MATERIALS AND
methodsThis study includes 208 children aged 6-14 years, distributed equally into CD patients and healthy controls. A parent completed and validated the interview questionnaire, which included the child's personal information and medical history. A dental examination was undertaken to measure possible recurrent aphthous stomatitis (RAS), dental enamel defects (DEDs), dental caries experience, and dental malocclusion. Data were analyzed using descriptive statistics and bivariate and multivariate analysis.
resultsTwo hundred and eight participants were included (104 CD patients and 104 controls). The mean age for CD patients was 10.67 ± 2.39 years and 10.69 ± 2.36 for the healthy controls. CD children had more RAS than controls (42.3% vs. 15.4%, P < 0.001) (OR = 4.03, 95% CI = 2.09-7.81) and more DEDs than healthy controls (70.2% vs. 34.6%, P < 0.001) (OR = 4.45, 95% CI = 2.48-7.97). No significant difference was found in the frequency of malocclusion between cases and controls.
conclusionSaudi Arabian children with CD had a greater number of clinical findings of RAS and DEDs than healthy controls. Pediatric dentists should consider the possibility of CD in child patients presenting with RAS or DEDs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.