Evidence map›Paper›PMID 34965480›Full record

ArticleJournal of clinical epidemiology2022

A cross sectional study found differential risks for COVID-19 seropositivity amongst health care professionals in Chile.

Marcela Zuñiga, Anne J Lagomarcino, Sergio Muñoz, Alfredo Peña Alonso, María Andrea Rodriguez, Miguel L O'Ryan

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Marcela ZuñigaHealth Care Networks Under Secretariat, Ministry of Health, Monjitas 565, Santiago, Chile.
Anne J LagomarcinoOffice of Innovation, Faculty of Medicine, Universidad de Chile, Avenida Independencia 1027, Independencia, Santiago, Chile.
Sergio MuñozDepartment of Public Health, CIGES, Faculty of Medicine, Universidad de La Frontera, Claro Solar 115, Temuco, Chile.
Alfredo Peña AlonsoManagement Control and Quality Department, Primary Care Division, Health Care Networks Under Secretariat, Ministry of Health, Monjitas 565, Santiago, Chile.
María Andrea RodriguezComputer Science Department, Universidad de Concepción, Edmundo Larenas 219, Concepción, Chile; Millennium Institute of Foundational Research on Data, Campus San Joaquín, Pontificia Universidad Católica de Chile, Vicuña Mackenna 4860, Macul, Chile.
Miguel L O'RyanMicrobiology and Mycology Program, Institute of Biomedical Sciences, Faculty of Medicine, Universidad de Chile, Avenida Independencia 1027, Independencia, Santiago, Chile; Millennium Institute on Immunology and Immunotherapy, Faculty of Medicine, Universidad de Chile, Avenida Independencia 1027, Independencia, Santiago, Chile. Electronic address: Moryan@uchile.cl.
Ministry of Health · CLMillennium Institute on Immunology and Immunotherapy · CLPontificia Universidad Católica de Chile · CLUniversidad de La Frontera · CLUniversity of Chile · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHealth care workers (HCWs) are at increased risk for SARS-CoV-2 infection, however not all face the same risk. We aimed to determine IgG/IgM prevalence and risk factors associated with seropositivity in Chilean HCWs. STUDY DESIGN AND

settingThis was a nationwide, cross-sectional study including a questionnaire and COVID-19 lateral flow IgG/IgM antibody testing. All HCWs in the Chilean public health care system were invited to participate following the country's first wave.

resultsIgG/IgM positivity in 85,529 HCWs was 7.2%, ranging from 1.6% to 12.4% between regions. Additionally, 9.7% HCWs reported a positive PCR of which 47% were seropositive. Overall, 10,863 (12.7%) HCWs were PCR and/or IgG/IgM positive. Factors independently associated with increased odds ratios (ORs) for seropositivity were: working in a hospital, night shifts, contact with Covid-19, using public transport, male gender, age>45, BMI ≥30, and reporting ≥2 symptoms. Stress and/or mental health disorder and smoking were associated with decreased ORs. These factors remained significant when including PCR positive cases in the model.

conclusionsHCWs in the hospital were at highest risk for COVID-19, and several independent risk factors for seropositivity and/or PCR positivity were identified.

Indexed as

COVID-19Antibodies, ViralChileCross-Sectional StudiesHealth PersonnelHumansMaleMiddle AgedSARS-CoV-2Seroepidemiologic StudiesAntibodies, ViralAntibody prevalenceAntibody testingCOVID-19Health care workersSARS-CoV-2Vaccine priority

Identifiers

PMID34965480
PMCPMC8710239
OpenAlexW4200516098

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.