ArticleCell reports2021
Dentate gyrus and CA3 GABAergic interneurons bidirectionally modulate signatures of internal and external drive to CA1.
Open access · goldAbstract read
In one paragraph
Article in Cell reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 36 citations in OpenAlex.
- Dentate gyrus interneurons modulate winner-take-all network dynamics in freely behaving mice.Neuron · 2026Article
- Behavioral impact of chemogenetic manipulations of 5-HT DRN neurons in transgenic Tph2-iCre rats.Psychopharmacology · 2026Article
- Review
- Medial entorhinal-hippocampal desynchronization parallels the emergence of memory impairment in a mouse model of Alzheimer's disease pathology.Cell reports · 2026Article
- Spectral dependence as a framework for neural coordination.Current research in neurobiology · 2026Article
- Segmentation and classification of hippocampal subregions using multi-task generative adversarial networks.Scientific reports · 2026Article
- Neuronal APOE4-induced early hippocampal network hyperexcitability in Alzheimer's disease pathogenesis.Nature aging · 2026Article
- Article
- Temporal Coding rather than Circuit Wiring allows Hippocampal CA3 Neurons to Dynamically Distinguish Different Cortical Inputs.bioRxiv : the preprint server for biology · 2026Article
- A hippocampal 'sharp-wave sleep' state that is dissociable from cortical sleep.Nature neuroscience · 2026Article
- Early-life cognitive intervention preserves brain function in aged TgF344-AD rats with sex-specific effects.iScience · 2026Article
- Generative emergence of non-local representations in the hippocampus.Nature communications · 2025Article
- Article
- Article
- Brief sleep disruption alters synaptic structures among hippocampal and neocortical somatostatin-expressing interneurons.bioRxiv : the preprint server for biology · 2025Article
- Dexmedetomidine Alleviates Hippocampal Tissue Damage in Rapid Eye Movement Sleep-Deprived Rats by Activating BDNF/TrkB Signaling Pathway.Nature and science of sleep · 2025Article
- Hippocampal structure, patterns of the calcium-binding proteins and neuron numbers in small echolocating bats.Frontiers in neuroanatomy · 2025Article
- Dentate gyrus is needed for memory retrieval.Molecular psychiatry · 2024Article
- Microglial AKAP8L: a key mediator in diabetes-associated cognitive impairment via autophagy inhibition and neuroinflammation triggering.Journal of neuroinflammation · 2024Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 3 institutions in 1 country.
Emily A Aery JonesGladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA 94158, USA; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA.
Antara RaoGladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA 94158, USA; Developmental & Stem Cell Biology Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA.
Misha ZilberterGladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA 94158, USA.
Biljana DjukicGladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA 94158, USA.
Jason S BantGladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA 94158, USA.
Anna K GillespieKavli Institute for Fundamental Neuroscience and Departments of Physiology and Psychiatry, University of California, San Francisco, San Francisco, CA 94143, USA.
Nicole KoutsodendrisGladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA 94158, USA; Developmental & Stem Cell Biology Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA.
Maxine NelsonGladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA 94158, USA; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA.
Seo Yeon YoonGladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA 94158, USA.
Ky HuangGladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA 94158, USA.
Heidi YuanGladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA 94158, USA.
Theodore M GillGladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA 94158, USA.
Yadong HuangGladstone Institute of Neurological Disease, Gladstone Institutes, San Francisco, CA 94158, USA; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA; Developmental & Stem Cell Biology Graduate Program, University of California, San Francisco, San Francisco, CA 94143, USA; Departments of Neurology and Pathology, University of California, San Francisco, San Francisco, CA 94143, USA; Gladstone Center for Translational Advancement, Gladstone Institutes, San Francisco, CA 94158, USA. Electronic address: yadong.huang@gladstone.ucsf.edu.
Loren M FrankKavli Institute for Fundamental Neuroscience and Departments of Physiology and Psychiatry, University of California, San Francisco, San Francisco, CA 94143, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address: loren.frank@ucsf.edu.
Gladstone Institutes · USHoward Hughes Medical Institute · USUniversity of California, San Francisco · US
Funding
Project 4: Cross-species Dissection of Cellular Response to APOE Genotype and AD Pathology Using Single-cell Multi-omicsP01AG073082 · NIA · J. DAVID GLADSTONE INSTITUTES · PI CORCES, MICHAEL RYAN · 2021 to 2025
$23.4MPREDOCTORAL TRAINING IN DEVELOPMENTAL BIOLOGYT32HD007470 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Todd Nystul · 1994 to 2026
$7.7MStudy ApoE4's Effects on Hippocampal Network Activity in Alzheimer's DiseaseR01AG055682 · NIA · J. DAVID GLADSTONE INSTITUTES · PI HUANG, YADONG · 2017 to 2021
$3.6MRoles of ApoE4 in Brain Aging and Alzheimer's DiseaseRF1AG055421 · NIA · J. DAVID GLADSTONE INSTITUTES · PI HUANG, YADONG · 2017 to 2017
$3.3MOptogenetic Study of ApoE4-Related Alzheimers DiseaseRF1AG047655 · NIA · J. DAVID GLADSTONE INSTITUTES · PI HUANG, YADONG, KREITZER, ANATOL · 2014 to 2014
$2.1MDetermining How Alzheimer's Disease Alters Hippocampal Network Signatures of Memory in Mouse ModelsF31AG057150 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AERY JONES, EMILY ASTER · 2017 to 2019
$69kNIA NIH HHS F31 AG057150NIA NIH HHS P01 AG073082NIA NIH HHS R01 AG055682NIA NIH HHS RF1 AG047655NIA NIH HHS RF1 AG055421NICHD NIH HHS T32 HD007470
Abstract
Specific classes of GABAergic neurons play specific roles in regulating information processing in the brain. In the hippocampus, two major classes, parvalbumin-expressing (PV
Indexed as
Action PotentialsAnimalsCA1 Region, HippocampalCA3 Region, HippocampalDentate GyrusEntorhinal CortexFemaleGABAergic NeuronsInterneuronsMaleMiceMice, Inbred C57BLSomatostatinSomatostatinCA1CA3dentate gyrusfast gammaGABAergic interneuronhippocampusparvalbuminsharp-wave rippleslow gammasomatostatintheta
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.