Evidence map›Paper›PMID 34965252›Full record

ArticlePloS one2021

Protocol of the Healthy Brain Study: An accessible resource for understanding the human brain and how it dynamically and individually operates in its bio-social context.

Healthy Brain Study consortium, Esther Aarts, Agnes Akkerman, Mareike Altgassen, Ronald Bartels, Becky Beckers, Kirsten Bevelander, Erik Bijleveld, Esmeralda Blaney Davidson, Annemarie Boleij and 78 more

Erratum issuedAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

88 authors.

Healthy Brain Study consortiumRadboud University, Nijmegen, The Netherlands
Esther AartsDonders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, The Netherlands
Agnes AkkermanInstitute for Management Research, Radboud University, Nijmegen, The Netherlands
Mareike AltgassenJohannes Gutenberg-University Mainz, Germany
Ronald BartelsRadboud University Medical Center, Nijmegen, The Netherlands
Becky BeckersBehavioural Science Institute, Radboud University, Nijmegen, The Netherlands
Kirsten BevelanderRadboud University Medical Center, Nijmegen, The Netherlands
Erik BijleveldBehavioural Science Institute, Radboud University, Nijmegen, The Netherlands
Esmeralda Blaney DavidsonRadboud University Medical Center, Nijmegen, The Netherlands
Annemarie BoleijRadboud University Medical Center, Nijmegen, The Netherlands
Janita BraltenRadboud University Medical Center, Nijmegen, The Netherlands
Toon CillessenBehavioural Science Institute, Radboud University, Nijmegen, The Netherlands
Jurgen ClaassenRadboud University Medical Center, Nijmegen, The Netherlands
Roshan CoolsDonders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands
Ineke CornelissenRadboud University Medical Center, Nijmegen, The Netherlands
Martin DreslerDonders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands
Thijs EijsvogelsRadboud University Medical Center, Nijmegen, The Netherlands
Myrthe FaberDonders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands
Guillén FernándezDonders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands
Bernd FignerDonders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, The Netherlands
Matthias FritscheDonders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, The Netherlands
Sascha FüllbrunnInstitute for Management Research, Radboud University, Nijmegen, The Netherlands
Surya GayetDonders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, The Netherlands
Marleen M. H. J. van GelderRadboud University Medical Center, Nijmegen, The Netherlands
Marcel van GervenDonders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, The Netherlands
Sabine GeurtsBehavioural Science Institute, Radboud University, Nijmegen, The Netherlands
Corina U. GrevenDonders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands
Martine GroefsemaBehavioural Science Institute, Radboud University, Nijmegen, The Netherlands
Koen HaakDonders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands
Peter HagoortMax Planck Institute for Psycholinguistics, Nijmegen, The Netherlands
Yvonne HartmanRadboud University Medical Center, Nijmegen, The Netherlands
Beatrice van der HeijdenInstitute for Management Research, Radboud University, Nijmegen, The Netherlands
Erno HermansDonders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands
Vivian HeuvelmansRadboud University Medical Center, Nijmegen, The Netherlands
Florian HintzMax Planck Institute for Psycholinguistics, Nijmegen, The Netherlands
Janet den HollanderRadboud University Medical Center, Nijmegen, The Netherlands
Anneloes M. HulsmanDonders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, The Netherlands
Sebastian IdesisCenter for Brain and Cognition, University Pompeu Fabra, Barcelona, Spain
Martin JaegerRadboud University Medical Center, Nijmegen, The Netherlands
Esther JanseCentre for Language Studies, Radboud University, Nijmegen, The Netherlands
Joost JanzingRadboud University Medical Center, Nijmegen, The Netherlands
Roy P. C. KesselsDonders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, The Netherlands
Johan C. KarremansBehavioural Science Institute, Radboud University, Nijmegen, The Netherlands
Willemien de KleijnSchool of Psychology and Artificial Intelligence, Radboud University, Nijmegen, The Netherlands
Marieke KleinRadboud University Medical Center, Nijmegen, The Netherlands
Floris KlumpersDonders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, The Netherlands
Nils KohnDonders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands
Hubert KorziliusInstitute for Management Research, Radboud University, Nijmegen, The Netherlands
Bas KrahmerRadboud University Medical Center, Nijmegen, The Netherlands
Floris de LangeDonders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, The Netherlands
Judith van LeeuwenDonders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands
Huaiyu LiuBehavioural Science Institute, Radboud University, Nijmegen, The Netherlands
Maartje LuijtenBehavioural Science Institute, Radboud University, Nijmegen, The Netherlands
Peggy MandersRadboud University Medical Center, Nijmegen, The Netherlands
Katerina ManevskaInstitute for Management Research, Radboud University, Nijmegen, The Netherlands
José P. MarquesDonders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, The Netherlands
Jon MatthewsRadboud University Medical Center, Nijmegen, The Netherlands
James M. McQueenDonders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, The Netherlands
Pieter MedendorpDonders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, The Netherlands
René MelisRadboud University Medical Center, Nijmegen, The Netherlands
Antje MeyerMax Planck Institute for Psycholinguistics, Nijmegen, The Netherlands
Joukje OostermanDonders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, The Netherlands
Lucy OverbeekRadboud University Medical Center, Nijmegen, The Netherlands
Marius PeelenDonders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, The Netherlands
Jean PopmaInterdisciplinary Hub for Security, Privacy and Data Governance, Radboud University, Nijmegen, The Netherlands
Geert PostmaInstitute for Molecules and Materials, Radboud University, Nijmegen, The Netherlands
Karin RoelofsDonders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, The Netherlands
Yvonne G. T. van RossenbergInstitute for Management Research, Radboud University, Nijmegen, The Netherlands
Gabi SchaapBehavioural Science Institute, Radboud University, Nijmegen, The Netherlands
Paul ScheepersRadboud University Medical Center, Nijmegen, The Netherlands
Luc SelenDonders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, The Netherlands
Marianne StarrenCentre for Language Studies, Radboud University, Nijmegen, The Netherlands
Dorine W. SwinkelsRadboud University Medical Center, Nijmegen, The Netherlands
Indira TendolkarDonders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands
Dick ThijssenRadboud University Medical Center, Nijmegen, The Netherlands
Hans TimmermanUniversity Medical Center Groningen, Groningen, The Netherlands
Rayyan TutunjiDonders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands
Anil TuladharDonders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands
Harm VelingBehavioural Science Institute, Radboud University, Nijmegen, The Netherlands
Maaike VerhagenBehavioural Science Institute, Radboud University, Nijmegen, The Netherlands
Jasper VerkroostRadboud University Medical Center, Nijmegen, The Netherlands
Jacqueline VinkBehavioural Science Institute, Radboud University, Nijmegen, The Netherlands
Vivian VriezekolkRadboud University Medical Center, Nijmegen, The Netherlands
Janna VrijsenDonders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands
Jana VyrastekovaInstitute for Management Research, Radboud University, Nijmegen, The Netherlands
Selina van der WalRadboud University Medical Center, Nijmegen, The Netherlands
Roel WillemsDonders Institute for Brain, Cognition and Behavior, Radboud University, Nijmegen, The Netherlands
Arthur WillemsenRadboud University Medical Center, Nijmegen, The Netherlands

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The endeavor to understand the human brain has seen more progress in the last few decades than in the previous two millennia. Still, our understanding of how the human brain relates to behavior in the real world and how this link is modulated by biological, social, and environmental factors is limited. To address this, we designed the Healthy Brain Study (HBS), an interdisciplinary, longitudinal, cohort study based on multidimensional, dynamic assessments in both the laboratory and the real world. Here, we describe the rationale and design of the currently ongoing HBS. The HBS is examining a population-based sample of 1,000 healthy participants (age 30-39) who are thoroughly studied across an entire year. Data are collected through cognitive, affective, behavioral, and physiological testing, neuroimaging, bio-sampling, questionnaires, ecological momentary assessment, and real-world assessments using wearable devices. These data will become an accessible resource for the scientific community enabling the next step in understanding the human brain and how it dynamically and individually operates in its bio-social context. An access procedure to the collected data and bio-samples is in place and published on https://www.healthybrainstudy.nl/en/data-and-methods/access. Trail registration: https://www.trialregister.nl/trial/7955.

Indexed as

Social EnvironmentAdultAffectBehaviorBrainCognitionCOVID-19FemaleHumansMaleNeuroimagingSensationSurveys and Questionnaires

Identifiers

PMID34965252
PMCPMC8716054

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.