Evidence map›Paper›PMID 34965215›Full record

ArticleAging2021

LINC00839 knockdown restrains the metastatic behavior of nasopharyngeal carcinoma by sponging miR-454-3p.

Feng Ying Zhang, Xia Li, Ting Ting Huang, Mei Ling Xiang, Lin Lin Sun, Zhao Lan Sun

Abstract read
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Feng Ying ZhangDepartment of Otorhinolaryngology, Weifang Hospital of Traditional Chinese Medicine, Weifang, Shandong, China.
Xia LiDepartment of Anesthesiology, Weifang Hospital of Traditional Chinese Medicine, Weifang, Shandong, China.
Ting Ting HuangDepartment of Otorhinolaryngology, Weifang Hospital of Traditional Chinese Medicine, Weifang, Shandong, China.
Mei Ling XiangDepartment of Otorhinolaryngology, Weifang Hospital of Traditional Chinese Medicine, Weifang, Shandong, China.
Lin Lin SunDepartment of Otorhinolaryngology, Weifang Hospital of Traditional Chinese Medicine, Weifang, Shandong, China.
Zhao Lan SunThe First Clinical Medical College of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long intergenic non-coding RNA 00839 (LINC00839) has been verified as a pro-metastasis factor in malignancies. However, the significance of LINC00839 in nasopharyngeal carcinoma (NPC) has yet to be illuminated, as well as its underlying mechanism. Here, we disclosed that LINC00839 is highly expressed in NPC. Deletion of LINC00839 suppresses NPC cells rapid growth, invasive capacity and EMT

Indexed as

Gene Knockdown TechniquesAnimalsCell ProliferationDown-RegulationHumansMiceMicroRNAsNasopharyngeal CarcinomaNasopharyngeal NeoplasmsNeoplasm MetastasisRNA, Long NoncodingUp-RegulationMicroRNAsMIRN454 microRNA, humanRNA, Long NoncodingEMTinvasionLINC00839miR-454-3pnasopharyngeal carcinoma

Identifiers

PMID34965215
PMCPMC8751606

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.