Evidence map›Paper›PMID 34965192›Full record

ArticleRNA biology2022

piRNAQuest V.2: an updated resource for searching through the piRNAome of multiple species.

Byapti Ghosh, Arijita Sarkar, Sudip Mondal, Namrata Bhattacharya, Sunirmal Khatua, Zhumur Ghosh

Open access · hybridAbstract read
In one paragraph

Article in RNA biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. RYR1Journal of translational medicine · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. piRNA associates with immune diseases.Cell communication and signaling : CCS · 2024
    Review
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Byapti GhoshDivision of Bioinformatics, Bose Institute, Kolkata, India.
Arijita SarkarDivision of Bioinformatics, Bose Institute, Kolkata, India.
Sudip MondalDepartment of Computer Science and Engineering, University of Calcutta, Kolkata, India.
Namrata BhattacharyaDepartment of Computer Science and Engineering, Indraprastha Institute of Information Technology, Delhi, India.
Sunirmal KhatuaDepartment of Computer Science and Engineering, University of Calcutta, Kolkata, India.
Zhumur GhoshDivision of Bioinformatics, Bose Institute, Kolkata, India.
Bose Institute · INUniversity of Calcutta · INIndraprastha Institute of Information Technology Delhi · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PIWI interacting RNAs (piRNAs) have emerged as important gene regulators in recent times. Since the release of our first version of piRNAQuest in 2014, lots of novel piRNAs have been annotated in different species other than human, mouse and rat. Such new developments in piRNA research have led us to develop an updated database piRNAQuest V.2. It consists of 92,77,689 piRNA entries for 25 new species of different phylum along with human, mouse and rat. Besides providing primary piRNA features which include their genomic location, with further information on piRNAs overlapping with repeat elements, pseudogenes and syntenic regions, etc., the novel features of this version includes (i) density based cluster prediction, (ii) piRNA expression profile across various healthy and disease systems and (iii) piRNA target prediction. The concept of density-based piRNA cluster identification is robust as it does not consider parametric distribution in its model. The piRNA expression profile for 21 disease systems including cancer have been hosted in addition to 32 tissue specific piRNA expression profile for various species. Further, the piRNA target prediction section includes both predicted and curated piRNA targets within eight disease systems and developmental stages of mouse testis. Further, users can visualize the piRNA-target duplex structure and the ping-pong signature pattern for all the ping-pong piRNA partners in different species. Overall, piRNAQuest V.2 is an updated user-friendly database which will serve as a useful resource to survey, search and retrieve information on piRNAs for multiple species. This freely accessible database is available at http://dibresources.jcbose.ac.in/zhumur/pirnaquest2.

Indexed as

SoftwareTranscriptomeAnimalsChromosome MappingComputational BiologyDatabases, GeneticGene AmplificationGene Expression ProfilingGenomicsHumansOrgan SpecificityRepetitive Sequences, Nucleic AcidRNA, Small InterferingSpecies SpecificityWeb BrowserRNA, Small Interferingping-pong piRNAspiRNA clusterpiRNA profilepiRNA targetPIWI interacting RNAs

Identifiers

PMID34965192
PMCPMC8786328
OpenAlexW4200561493

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.