Evidence map›Paper›PMID 34965182›Full record

ArticleRNA biology2022

RNA polymerase II is recruited to DNA double-strand breaks for dilncRNA transcription in

Romy Böttcher, Ines Schmidts, Volker Nitschko, Petar Duric, Klaus Förstemann

Open access · hybridAbstract read
In one paragraph

Article in RNA biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. DNA topological regulation in RNA polymerase II transcription.Cellular & molecular biology letters · 2026
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Romy BöttcherDepartment. Of Biochemistry and Gene Center, Ludwig-Maximilians-Universität München, München, Germany.
Ines SchmidtsDepartment. Of Biochemistry and Gene Center, Ludwig-Maximilians-Universität München, München, Germany.
Volker NitschkoDepartment. Of Biochemistry and Gene Center, Ludwig-Maximilians-Universität München, München, Germany.
Petar DuricDepartment. Of Biochemistry and Gene Center, Ludwig-Maximilians-Universität München, München, Germany.
Klaus FörstemannDepartment. Of Biochemistry and Gene Center, Ludwig-Maximilians-Universität München, München, Germany.
Ludwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA double-strand breaks are among the most toxic lesions that can occur in a genome and their faithful repair is thus of great importance. Recent findings have uncovered local transcription that initiates at the break and forms a non-coding transcript, called damage-induced long non-coding RNA (dilncRNA), which helps to coordinate the DNA transactions necessary for repair. We provide nascent RNA sequencing-based evidence that RNA polymerase II transcribes the dilncRNA in

Indexed as

DNA Breaks, Double-StrandedTranscription, GeneticAnimalsDNA RepairDrosophilaGene Expression RegulationIntronsProtein BindingRNA, Long NoncodingRNA Polymerase IIRNA Polymerase IIIRNA, Small InterferingRNA SplicingSequence Analysis, DNARNA, Long NoncodingRNA Polymerase IIRNA Polymerase IIIRNA, Small Interferingantisense transcriptiondilncRNADNA double-strand break (DSB)RNA polymerase IIRNA polymerase IIIsiRNA silencingspliceosomesplicing

Identifiers

PMID34965182
PMCPMC8786327
OpenAlexW4226270949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.