Evidence map›Paper›PMID 34965179›Full record

ArticleHuman vaccines & immunotherapeutics2021

An exploratory study to assess patterns of influenza- and pneumonia-related mortality among the Italian elderly.

Elettra Fallani, Andrea Orsi, Alessio Signori, Giancarlo Icardi, Alexander Domnich

Open access · bronzeAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Elettra FallaniSeqirus S.R.L., Monteriggioni, Italy.ORCID 0000-0002-7326-9102
Andrea OrsiDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.ORCID 0000-0002-2433-9610
Alessio SignoriDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.ORCID 0000-0001-6289-9144
Giancarlo IcardiDepartment of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.ORCID 0000-0002-8463-8487
Alexander DomnichHygiene Unit, San Martino Policlinico Hospital - IRCCS for Oncology and Neurosciences, Genoa, Italy.ORCID 0000-0001-9608-8892
Ospedale Policlinico San Martino · ITUniversity of Genoa · ITUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Older adults are at disproportionately high risk of severe influenza-related outcomes and represent the main target of the annual influenza vaccination. The protective effect of seasonal influenza vaccination on the observed mortality indicators is controversial. In this ecological study, spatiotemporal patterns of pneumonia- and influenza-related mortality registered in the Italian elderly over seven (2011-2017) consecutive seasons were explored and the epidemiological association between the observed local pneumonia- and influenza-related mortality and influenza vaccination campaign features were modeled by using both fixed- and random-effects panel regression models. The descriptive spatiotemporal analysis showed a clear North-South gradient, where northern regions tended to report more pneumonia- and influenza-related deaths. After adjustment for potential confounders, it was found that each 1% increase in influenza vaccination coverage rate would be associated (

Indexed as

Influenza, HumanInfluenza VaccinesPneumoniaAdjuvants, ImmunologicAgedHumansPolysorbatesSqualeneVaccinationAdjuvants, ImmunologicInfluenza VaccinesPolysorbatesSqualeneadjuvanted influenza vaccineecological studyelderlyInfluenzaItalyspatial analysisvaccine

Identifiers

PMID34965179
PMCPMC8916782
OpenAlexW4200161571

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.