Evidence map›Paper›PMID 34964633›Full record

ArticleMolecular pharmaceutics2022

Machine Learning Models for

Thomas R Lane, Fabio Urbina, Laura Rank, Jacob Gerlach, Olga Riabova, Alexander Lepioshkin, Elena Kazakova, Anthony Vocat, Valery Tkachenko, Stewart Cole and 2 more

Abstract read
In one paragraph

Article in Molecular pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. 1-Sulfonyl-3-amino-1ACS omega · 2023
    Article
  13. Article
  14. Article
  15. Comparing LDJournal of chemical health & safety · 2023
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Thomas R LaneCollaborations Pharmaceuticals, Inc., 840 Main Campus Drive, Lab 3510, Raleigh, North Carolina 27606, United States.
Fabio UrbinaCollaborations Pharmaceuticals, Inc., 840 Main Campus Drive, Lab 3510, Raleigh, North Carolina 27606, United States.
Laura RankCollaborations Pharmaceuticals, Inc., 840 Main Campus Drive, Lab 3510, Raleigh, North Carolina 27606, United States.
Jacob GerlachCollaborations Pharmaceuticals, Inc., 840 Main Campus Drive, Lab 3510, Raleigh, North Carolina 27606, United States.
Olga RiabovaResearch Center of Biotechnology RAS, Moscow 119071, Russia.
Alexander LepioshkinResearch Center of Biotechnology RAS, Moscow 119071, Russia.
Elena KazakovaResearch Center of Biotechnology RAS, Moscow 119071, Russia.
Anthony VocatGlobal Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne 1015, Switzerland.
Valery TkachenkoScience Data Experts, 14909 Forest Landing Cir, Rockville, Maryland 20850, United States.
Stewart ColeInstitut Pasteur, Paris 75015, France.
Vadim MakarovResearch Center of Biotechnology RAS, Moscow 119071, Russia.
Sean EkinsCollaborations Pharmaceuticals, Inc., 840 Main Campus Drive, Lab 3510, Raleigh, North Carolina 27606, United States.ORCID 0000-0002-5691-5790

Funding

Centralized assay datasets for modelling support of small drug discovery organizationsR44GM122196 · NIGMS · COLLABORATIONS PHARMACEUTICALS, INC. · PI EKINS, SEAN · 2018 to 2022
$3.3M
MegaTox for analyzing and visualizing data across different screening systemsR43ES031038 · NIEHS · COLLABORATIONS PHARMACEUTICALS, INC. · PI EKINS, SEAN · 2019 to 2020
$349k
MegaPredict for predicting natural product uses and their drug interactionsR43AT010585 · NCCIH · COLLABORATIONS PHARMACEUTICALS, INC. · PI EKINS, SEAN · 2019 to 2020
$225k
NCCIH NIH HHS R43 AT010585NIEHS NIH HHS R43 ES031038NIGMS NIH HHS R44 GM122196
6 · The paper itself

Abstract

Tuberculosis (TB) is a major global health challenge, with approximately 1.4 million deaths per year. There is still a need to develop novel treatments for patients infected with

Indexed as

Mycobacterium tuberculosisTuberculosisAntitubercular AgentsBayes TheoremHumansMachine LearningAntitubercular Agentsassay centraldeep learningdrug discoverymachine learningmolecular featuressupport vector machinetuberculosis

Identifiers

PMID34964633
PMCPMC9121329

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.