ArticlePaediatric and perinatal epidemiology2022
Antepartum severe maternal morbidity: A population-based study of risk factors and delivery outcomes.
Article in Paediatric and perinatal epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Global burden of potentially life-threatening maternal conditions: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2024Pooled it
- Severe maternal morbidity in patients with pre-existing diseases: a prospective observational cohort study (ForMaT trial).Scientific reports · 2026Observational
- Severe Maternal Morbidity Among Adolescents Aged 10-19 in California, 2001-2020.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2026Article
- Incidence, Risk Factors and Outcomes of SARS-CoV-2 Infection in Pregnant Women: The COROPREG Population-Based Study.Paediatric and perinatal epidemiology · 2025Article
- Determinants of potential life-threatening maternal conditions (PLTCs) in Tigray, northern Ethiopia: a case‒control study.Scientific reports · 2024Article
- Antepartum severe maternal morbidity: A population-based study of risk factors and delivery outcomes.Paediatric and perinatal epidemiology · 2022Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSevere maternal morbidity (SMM) is a key indicator of maternal health. Generally explored without distinction by the timing of the event, it mainly reflects postpartum SMM. Although antepartum (pre-labour) SMM presents specific challenges in its need to optimise the risk-benefit balance for both mother and foetus, its features remain inadequately explored.
objectivesWe explored risk factors of antepartum SMM and described adverse delivery and neonatal outcomes associated with antepartum SMM.
methodsWe designed a population-based nested case-control study based on data from the EPIMOMS study (119 maternity hospitals of 6 French regions, 2012-2013, N = 182,309 deliveries in the source cohort). This study included all women with antepartum SMM (cases, n = 601) compared to a randomly selected sample of women who gave birth without SMM in the same hospitals (controls, n = 3651). Antepartum SMM risk factors were identified with multivariable logistic regression following imputations for missing data.
resultsAntepartum SMM complicated 0.33% (95% confidence interval [CI] 0.30, 0.36) of pregnancies. Antepartum SMM risk factors were maternal age ≥35 years (adjusted odds ratio [OR] 1.55, 95% CI 1.22, 1.97), increased body mass index (OR for 5 kg/m
conclusionsAntepartum SMM is rare but associated with increased rates of adverse delivery and neonatal outcomes.
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