Evidence map›Paper›PMID 34964481›Full record

ArticleHistology and histopathology2022

Pathological diagnosis, differential diagnosis and origin investigation of easily misdiagnosed adult gastric duplication cysts.

Fangfang Liu, Huimin Zhao

Abstract read
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In one paragraph

Article in Histology and histopathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Gastric duplication cyst in an adult woman: a case report.Journal of surgical case reports · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Fangfang LiuDepartment of Pathology, Peking University People's Hospital, Beijing, China. liufangfang@pkuph.edu.cn.
Huimin ZhaoDepartment of Pathology, Peking University People's Hospital, Beijing, China.
Peking University · CN

Funding

Beijing Natural Science Foundation 7172223National Natural Science Foundation of China 81672805
6 · The paper itself

Abstract

objectivesTo study diagnosis, differential diagnosis, and origin of easily misdiagnosed adult gastric duplication cysts.

methodsSix cases with GDCs were studied using immunohistochemical methods to research the expression of tumor markers.

resultsMost GDCs were located in the abdominal cavity outside the digestive organs. The cyst wall tissues included a repetition of the full-thickness structure of the stomach wall that was lined by a variety of different epithelia. The expression of CK7 was positive in all epithelia (6/6), while CK7 expression was positive in cardia glands in 5/5 and positive in fundus glands in 1/5. CK 20 was 100% (4/4) positively expressed in the SCE, 100% (3/3) negative in the CCE, and in the SE. It was also expressed positively 100% (5/5) in fundus glands and 80% (4/5) in cardia glands. Both CK7 and CK20 were negatively expressed in the pyloric glands in case 3. The expression of MUC1 was positive in all epithelia and glands, whereas MUC2 expression was negative. MUC5AC was expressed differently in epithelia and glands.

conclusionsGDCs can originate from the antrum or the fundus of the stomach. Tumor markers can help diagnosis and differential diagnosis. This study may help to improve clinical precision treatment.

Indexed as

CystsStomach NeoplasmsAdultBiomarkers, TumorDiagnosis, DifferentialDiagnostic ErrorsHumansKeratin-7Biomarkers, TumorKeratin-7

Identifiers

PMID34964481
OpenAlexW4200266791

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.