Evidence map›Paper›PMID 34964155›Full record

ArticleScandinavian journal of immunology2022

Prognostic value and predictive biomarkers of phenotypes of tumour-associated macrophages in colorectal cancer.

Yu Kou, Zhuoqun Li, Qidi Sun, Shengnan Yang, Yunshuai Wang, Chen Hu, Huijie Gu, Huangjian Wang, Hairong Xu, Yan Li and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scandinavian journal of immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  16. Relationship Between Infiltration of CD163+ TAMs, FoxP3+ Tregs, or CD66b+ TANs and Cell Differentiation in Colorectal Cancer Tissues.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023
    Article
  17. Two tripartite classification systems of CD86Frontiers in immunology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yu KouJiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Medical College of Yangzhou University, Yangzhou, China.ORCID https://orcid.org/0000-0003-3387-8322
Zhuoqun LiJiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Medical College of Yangzhou University, Yangzhou, China.
Qidi SunJiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Medical College of Yangzhou University, Yangzhou, China.
Shengnan YangJiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Medical College of Yangzhou University, Yangzhou, China.
Yunshuai WangDepartment of General Surgery, Luoyang Central Hospital Affiliated of Zhengzhou University, Luoyang, China.
Chen HuJiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Medical College of Yangzhou University, Yangzhou, China.
Huijie GuJiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Medical College of Yangzhou University, Yangzhou, China.
Huangjian WangDepartment of General Surgery, Luoyang Central Hospital Affiliated of Zhengzhou University, Luoyang, China.
Hairong XuJiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Medical College of Yangzhou University, Yangzhou, China.
Yan LiJiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, Medical College of Yangzhou University, Yangzhou, China.
Baowei HanDepartment of General Surgery, Luoyang Central Hospital Affiliated of Zhengzhou University, Luoyang, China.

Funding

Key Scientific and Technological projects of Henan Province 192102310395Medical Science and Technology Research Program of Henan Province 2018020893Medical Science and Technology Research Program of Henan Province 2018020898National Natural Science Foundation of China 81803780Natural Science Foundation of Jiangsu Province BK20180928
6 · The paper itself

Abstract

backgroundThe roles of different subtypes of tumour-associated macrophages (TAMs) in predicting the prognosis of colorectal cancer (CRC) remain controversial. In this study, different subtypes of TAMs were investigated as prognostic and predictive biomarkers for CRC.

methodsExpressions of CD68, CD86 and CD163 were investigated by immunohistochemistry (IHC) and immunofluorescence (IF), and the correlation between the expression of CD86 and CD163 was calculated in colorectal cancer tissues from 64 CRC patients.

resultsThe results showed that high expressions of CD86

conclusionsThese results indicate that CD86

Indexed as

Colorectal NeoplasmsTumor-Associated MacrophagesAntigens, Differentiation, MyelomonocyticBiomarkersBiomarkers, TumorHumansMacrophagesPhenotypePrognosisAntigens, Differentiation, MyelomonocyticBiomarkersBiomarkers, Tumorbiomarkercolorectal cancertumour-associated macrophages

Identifiers

PMID34964155
PMCPMC9286461

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.