Evidence map›Paper›PMID 34964046›Full record

ArticleMachine learning in medical imaging. MLMI (Workshop)2021

SkullEngine: A Multi-Stage CNN Framework for Collaborative CBCT Image Segmentation and Landmark Detection.

Qin Liu, Han Deng, Chunfeng Lian, Xiaoyang Chen, Deqiang Xiao, Lei Ma, Xu Chen, Tianshu Kuang, Jaime Gateno, Pew-Thian Yap and 1 more

Abstract read
In one paragraph

Article in Machine learning in medical imaging. MLMI (Workshop), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  13. Patient-specific reference model estimation for orthognathic surgical planning.International journal of computer assisted radiology and surgery · 2024
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

11 authors.

Qin LiuDepartment of Radiology and Biomedical Research Imaging Center (BRIC), University of North Carolina at Chapel Hill, NC, USA.
Han DengDepartment of Oral and Maxillofacial Surgery, Houston Methodist Hospital, TX, USA.
Chunfeng LianDepartment of Radiology and Biomedical Research Imaging Center (BRIC), University of North Carolina at Chapel Hill, NC, USA.
Xiaoyang ChenDepartment of Radiology and Biomedical Research Imaging Center (BRIC), University of North Carolina at Chapel Hill, NC, USA.
Deqiang XiaoDepartment of Radiology and Biomedical Research Imaging Center (BRIC), University of North Carolina at Chapel Hill, NC, USA.
Lei MaDepartment of Radiology and Biomedical Research Imaging Center (BRIC), University of North Carolina at Chapel Hill, NC, USA.
Xu ChenDepartment of Radiology and Biomedical Research Imaging Center (BRIC), University of North Carolina at Chapel Hill, NC, USA.
Tianshu KuangDepartment of Oral and Maxillofacial Surgery, Houston Methodist Hospital, TX, USA.
Jaime GatenoDepartment of Oral and Maxillofacial Surgery, Houston Methodist Hospital, TX, USA.
Pew-Thian YapDepartment of Radiology and Biomedical Research Imaging Center (BRIC), University of North Carolina at Chapel Hill, NC, USA.
James J XiaDepartment of Oral and Maxillofacial Surgery, Houston Methodist Hospital, TX, USA.

Funding

Outcome-Driven Approach to Minimize the Risks of Facial Distortion Following CMF SurgeryR01DE021863 · NIDCR · METHODIST HOSPITAL RESEARCH INSTITUTE · PI GATENO, JAIME · 2013 to 2025
$5.1M
A Novel Imaging Informatics Platform for Craniomaxillofacial SurgeryR01DE022676 · NIDCR · METHODIST HOSPITAL RESEARCH INSTITUTE · PI GATENO, JAIME · 2011 to 2020
$4.0M
Learning-Based Approach for Personalized Craniomaxillofacial Surgical PlanningR01DE027251 · NIDCR · METHODIST HOSPITAL RESEARCH INSTITUTE · PI GATENO, JAIME · 2017 to 2021
$2.9M
NIDCR NIH HHS R01 DE021863NIDCR NIH HHS R01 DE022676NIDCR NIH HHS R01 DE027251
6 · The paper itself

Abstract

Accurate bone segmentation and landmark detection are two essential preparation tasks in computer-aided surgical planning for patients with craniomaxillofacial (CMF) deformities. Surgeons typically have to complete the two tasks manually, spending ~12 hours for each set of CBCT or ~5 hours for CT. To tackle these problems, we propose a multi-stage coarse-to-fine CNN-based framework, called SkullEngine, for high-resolution segmentation and large-scale landmark detection through a collaborative, integrated, and scalable JSD model and three segmentation and landmark detection refinement models. We evaluated our framework on a clinical dataset consisting of 170 CBCT/CT images for the task of segmenting 2 bones (midface and mandible) and detecting 175 clinically common landmarks on bones, teeth, and soft tissues. Experimental results show that SkullEngine significantly improves segmentation quality, especially in regions where the bone is thin. In addition, SkullEngine also efficiently and accurately detect all of the 175 landmarks. Both tasks were completed simultaneously within 3 minutes regardless of CBCT or CT with high segmentation quality. Currently, SkullEngine has been integrated into a clinical workflow to further evaluate its clinical efficiency.

Indexed as

Cone-Beam Computed Tomography (CBCT) ImageLandmark DetectionSegmentation

Identifiers

PMID34964046
PMCPMC8712093

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.