ArticleACS omega2021
Stability of Chlorogenic Acid from Artemisiae Scopariae Herba Enhanced by Natural Deep Eutectic Solvents as Green and Biodegradable Extraction Media.
Article in ACS omega, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed, 22 citations in OpenAlex.
- Recent Advances in Chlorogenic Acids for Food Preservation and Shelf-Life Extension.Antioxidants (Basel, Switzerland) · 2026Review
- Sichen Formula Ameliorates Lipopolysaccharide-Induced Acute Lung Injury via Blocking the TLR4 Signaling Pathways.Drug design, development and therapy · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A green and inexpensive natural deep eutectic solvent (NADES) was screened and integrated with an ultrasonic technique for extracting chlorogenic acid (CGA) from artemisiae scopariae herba. Response surface methodology was employed to investigate significant factors and optimize their influence. Proline-malic acid exhibited an excellent extraction capacity with a yield of 28.23 mg/g under the optimal conditions of water content of 15% (wt), solid-liquid ratio of 1.0/10 (g/mL), ultrasonic power of 300 W, and extraction time of 25 min. Simultaneously, the stability and antioxidant activity analysis exhibited a better performance of CGA in NADES than that in water and ethanol. The hydrogen-bonding interaction between CGA and natural deep eutectic molecules enhanced the stability and meanwhile protected the antioxidant activity of CGA.
Identifiers
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Registered trials
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