Evidence map›Paper›PMID 34963858›Full record

ReviewCureus2021

Chronic Pain: A Complex Condition With a Multi-Tangential Approach.

Iljena Kela, Chandra L Kakarala, Mohammad Hassan, Rishab Belavadi, Sri Vallabh Reddy Gudigopuram, Ciri C Raguthu, Harini Gajjela, Ibrahim Sange

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Neurosurgical management for chronic and end-of-life pain in children: A systematic review.Pain practice : the official journal of World Institute of Pain · 2025
    Pooled it
  2. Review
  3. Review
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  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 5 countries.

Iljena KelaFamily Medicine, Jagiellonian University Medical College, Krakow, POL.
Chandra L KakaralaInternal Medicine, Jawaharlal Institute of Post-Graduate Medical Education and Research (JIPMER), Puducherry, IND.
Mohammad HassanInternal Medicine, Mohiuddin Islamic Medical College, Mirpur, PAK.
Rishab BelavadiSurgery, Jawaharlal Institute of Post-Graduate Medical Education and Research (JIPMER), Puducherry, IND.
Sri Vallabh Reddy GudigopuramResearch, Our Lady of Fatima University College of Medicine, Manila, PHL.
Ciri C RaguthuResearch, Tianjin Medical University, Tianjin, CHN.
Harini GajjelaResearch, Our Lady of Fatima University College of Medicine Valenzuela, Metro Manila, PHL.
Ibrahim SangeResearch, K. J. Somaiya Medical College, Mumbai, IND.
Our Lady of Fatima University · PHK J Somaiya Medical College · INJawaharlal Institute of Post Graduate Medical Education and Research · INMohi-ud-Din Islamic University · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic pain is known as ongoing pain that lasts longer than three months with increasing healing time. It is approximated that 20% of adults of different sexes, races, and socioeconomic backgrounds fall victim to chronic pain. It is a result of several factors and can have lifelong effects. Pain is a complex matter to measure; therefore, the physician needs to understand the patient's health state to create a management plan tending to each issue adequately. There are many complications of such pain, and it can interfere terribly with an individual's quality of life. This article has reviewed the complex pathogenesis of chronic pain and the spectrum of non-pharmacologic modalities and pharmacological treatment options. It has also explored the efficacy of certain drugs and underlined the importance of nonpharmacological options such as physical exercise, cognitive therapy, and physical modalities to treat chronic pain and all the conditions that accompany this disorder.

Indexed as

chronic painchronic pain managementchronic pain treatmentneuropathic painneuropathic pain treatmentnociceptive painnonpharmacological treatment of chronic painpharmacological management of chronic pain

Identifiers

PMID34963858
PMCPMC8703086
OpenAlexW3215565392

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.